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DOK1 antibody

DOK1 Reactivity: Human, Mouse, Rat IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN966767
  • Target See all DOK1 Antibodies
    DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))
    Reactivity
    • 94
    • 51
    • 38
    • 7
    • 6
    • 6
    • 4
    • 2
    Human, Mouse, Rat
    Host
    • 108
    • 2
    Rabbit
    Clonality
    • 108
    • 2
    Polyclonal
    Conjugate
    • 48
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This DOK1 antibody is un-conjugated
    Application
    • 91
    • 37
    • 34
    • 18
    • 13
    • 13
    • 13
    • 10
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Specificity
    P62Dok (Ab-398) antibody detects endogenous levels of total p62Dok protein.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogen
    The antiserum was produced against synthesized non-phosphopeptide derived from human p62Dok around the phosphorylation site of tyrosine 398 (E-G-YP-E-L).
    Top Product
    Discover our top product DOK1 Primary Antibody
  • Application Notes
    WB: 1:500~1:1000
    IHC: 1:50~1:100.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    100ug/100ul.
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Simoncic, Bourdeau, Lee-Loy, Rohrschneider, Tremblay, Stanley, McGlade: "T-cell protein tyrosine phosphatase (Tcptp) is a negative regulator of colony-stimulating factor 1 signaling and macrophage differentiation." in: Molecular and cellular biology, Vol. 26, Issue 11, pp. 4149-60, (2006) (PubMed).

    Yopp, Ochando, Mao, Ledgerwood, Ding, Bromberg: "Sphingosine 1-phosphate receptors regulate chemokine-driven transendothelial migration of lymph node but not splenic T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 5, pp. 2913-24, (2005) (PubMed).

    Dubé, Cheng, Tremblay: "The role of protein tyrosine phosphatase 1B in Ras signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 7, pp. 1834-9, (2004) (PubMed).

    Wick, Dong, Hu, Langlais, Liu: "Insulin receptor-mediated p62dok tyrosine phosphorylation at residues 362 and 398 plays distinct roles for binding GTPase-activating protein and Nck and is essential for inhibiting insulin-stimulated activation of Ras and Akt." in: The Journal of biological chemistry, Vol. 276, Issue 46, pp. 42843-50, (2001) (PubMed).

  • Target
    DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))
    Alternative Name
    p62Dok (DOK1 Products)
    Synonyms
    P62DOK antibody, Dok-1 antibody, AW557123 antibody, p62DOK antibody, dok1 antibody, zgc:76914 antibody, docking protein 1 antibody, docking protein 1b antibody, DOK1 antibody, Dok1 antibody, dok1b antibody
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