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|+1 404 474 4654|
|+1 888 205 9894 (TF)|
P21-Activated Kinase 1 (PAK1) (pThr212) antibody
|Synonyms||PAKalpha, MGC130000, MGC130001, Paka, PAK-1, AW045634, PAK1, MGC83445, MGC139676|
Human, Mouse (Murine), Rat (Rattus)
Alternatives Immunohistochemistry (IHC)
|3 references available|
|Price||385.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 5 to 7 Business Days|
|Immunogen||The antiserum was produced against synthesized phosphopeptide derived from human PAK1 around the phosphorylation site of threonine 212 (P-V-TP-P-T).|
|Specificity||PAK1 (phospho-Thr212) antibody detects endogenous levels of PAK1 only when phosphorylated at threonine 212.|
|Purification||The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation.|
|Buffer||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol|
|Preservative||0.02% Sodium Azide|
|Storage||Store at -20°C/1 year.|
|Research Area||Cancer, Apoptosis/Necrosis, Kinases/Phosphatases|
|Restrictions||For Research Use only|
Rashid, Banerjee, Nikolic: "Phosphorylation of Pak1 by the p35/Cdk5 kinase affects neuronal morphology." in: The Journal of biological chemistry, Vol. 276, Issue 52, pp. 49043-52, 2001 (PubMed).
Thiel, Reeder, Pfaff et al.: "Cell cycle-regulated phosphorylation of p21-activated kinase 1." in: Current biology : CB, Vol. 12, Issue 14, pp. 1227-32, 2002 (PubMed).
Alexander, Yang, Hinds: "Cellular senescence requires CDK5 repression of Rac1 activity." in: Molecular and cellular biology, Vol. 24, Issue 7, pp. 2808-19, 2004 (PubMed).