Paxillin (PXN) (pTyr31) antibody

Details for Product No. ABIN966808
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Antigen
Synonyms CG18061, CG18576, CG31794, CT40481, CT42454, DPaxillin, DPxn, DPxn37, Dmel\\CG31794, Dpax, DpaxA, PDLP, dPax, pax, PXN, LOC100220858, AW108311, AW123232, Pax, wu:fw71f12
Epitope
pTyr31
(46), (39), (29), (25), (21), (18), (14), (10), (9), (7), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(308), (172), (162), (48), (39), (25), (2), (1), (1)
Host
Rabbit
(304), (32), (1)
Conjugate
Un-conjugated
(8), (8), (8), (7), (7), (7), (7), (7), (7), (7), (7), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC)
(246), (90), (70), (62), (62), (40), (24), (17), (4), (4), (3), (1)
Pubmed 2 references available
Quantity 100 µg
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Catalog No. ABIN966808
385.00 $
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Paxillin around the phosphorylation site of tyrosine 31 (T-P-YP-S-Y).
Specificity Paxillin (phospho-Tyr31) antibody detects endogenous levels of Paxillin only when phosphorylated at tyrosine 31.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Alternative Name Paxillin
Research Area Cancer, Extracellular Matrix
Application Notes WB: 1:500~1:1000.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Fleming, Bauersachs, Schäfer et al.: "Isometric contraction induces the Ca2+-independent activation of the endothelial nitric oxide synthase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 3, pp. 1123-8, 1999 (PubMed).

Davidson, Veillette: "PTP-PEST, a scaffold protein tyrosine phosphatase, negatively regulates lymphocyte activation by targeting a unique set of substrates." in: The EMBO journal, Vol. 20, Issue 13, pp. 3414-26, 2001 (PubMed).

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