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PCNA antibody (C-Term, ubLys164)

PCNA Reactivity: Human, Rat IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN966812
  • Target See all PCNA Antibodies
    PCNA (Proliferating Cell Nuclear Antigen (PCNA))
    Binding Specificity
    • 16
    • 16
    • 16
    • 15
    • 12
    • 10
    • 8
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term, ubLys164
    Reactivity
    • 216
    • 152
    • 152
    • 57
    • 32
    • 28
    • 23
    • 19
    • 19
    • 18
    • 18
    • 14
    • 11
    • 11
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat
    Host
    • 142
    • 87
    • 3
    Rabbit
    Clonality
    • 141
    • 90
    • 1
    Polyclonal
    Conjugate
    • 116
    • 17
    • 14
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PCNA antibody is un-conjugated
    Application
    • 198
    • 68
    • 65
    • 60
    • 58
    • 49
    • 49
    • 40
    • 31
    • 16
    • 15
    • 11
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Immunogen
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-residues of human PCNA (proliferating cell nuclear antigen)
    Note: Antigen containing K164 amino group with the ubiquitin c-terminal 7-mer peptide bound: CLRLRGG
    Top Product
    Discover our top product PCNA Primary Antibody
  • Restrictions
    For Research Use only
  • Storage
    4 °C
  • Kweekel, Antonini, Nortier, Punt, Gelderblom, Guchelaar: "Explorative study to identify novel candidate genes related to oxaliplatin efficacy and toxicity using a DNA repair array." in: British journal of cancer, Vol. 101, Issue 2, pp. 357-62, (2009) (PubMed).

    Niwa, Miwa, Kuzuya, Iwasaki, Haneda, Ueki, Katayama, Hiramitsu, Goto, Nagasaka, Watarai, Uchida, Nakao, Kobayashi: "Stimulation index for PCNA mRNA in peripheral blood as immune function monitoring after renal transplantation." in: Transplantation, Vol. 87, Issue 9, pp. 1411-4, (2009) (PubMed).

    Michiels, Laplanche, Boulet, Dessen, Guillonneau, Méjean, Desgrandchamps, Lathrop, Sarasin, Benhamou: "Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk." in: Carcinogenesis, Vol. 30, Issue 5, pp. 763-8, (2009) (PubMed).

    Canova, Hashibe, Simonato, Nelis, Metspalu, Lagiou, Trichopoulos, Ahrens, Pigeot, Merletti, Richiardi, Talamini, Barzan, Macfarlane, Macfarlane, Holcátová, Bencko, Benhamou, Bouchardy, Kjaerheim et al.: "Genetic associations of 115 polymorphisms with cancers of the upper aerodigestive tract across 10 European countries: the ARCAGE project. ..." in: Cancer research, Vol. 69, Issue 7, pp. 2956-65, (2009) (PubMed).

    Chen, Pan, Hurwitz: "Sequence and expression in Escherichia coli of the 40-kDa subunit of activator 1 (replication factor C) of HeLa cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 7, pp. 2516-20, (1992) (PubMed).

    Webb, Parsons, Chenevix-Trench: "Localization of the gene for human proliferating nuclear antigen/cyclin by in situ hybridization." in: Human genetics, Vol. 86, Issue 1, pp. 84-6, (1991) (PubMed).

  • Target
    PCNA (Proliferating Cell Nuclear Antigen (PCNA))
    Alternative Name
    PCNA (PCNA Products)
    Synonyms
    PCNAR antibody, Pcna/cyclin antibody, pcna antibody, AO090003000846 antibody, 53/13 antibody, CG9193 antibody, DmPCNA antibody, Dmel\\CG9193 antibody, MUS209 antibody, Mus209 antibody, PCNA antibody, PCNA/mus209 antibody, Pcna antibody, dPCNA antibody, l(2)02448 antibody, l(2)56F antibody, l(2)56Fa antibody, l(2)s1534 antibody, cb16 antibody, fb36g03 antibody, wu:fa28e03 antibody, wu:fb36g03 antibody, pcna-A antibody, proliferating cell nuclear antigen antibody, DNA polymerase III sliding clamp antibody, Proliferating cell nuclear antigen antibody, Proliferating cell nuclear antigen-like antibody, proliferating cell nuclear antigen L homeolog antibody, proliferating cell nuclear antigen 1 antibody, PCNA antibody, Pcna antibody, pcna antibody, MMP_RS08810 antibody, ANI_1_512014 antibody, AOR_1_1500154 antibody, MGC53867 antibody, pcna.L antibody, pcna1 antibody, LOC106420145 antibody, pcn1 antibody
    Background
    The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
    Pathways
    Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy
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