Phosphatase and Tensin Homolog (PTEN) (pSer370) antibody
| Antigen | Phosphatase and Tensin Homolog (PTEN) |
| Synonyms | BZS, MHAM, TEP1, MMAC1, PTEN1, 10q23del, MGC11227, AI463227, MGC183880, 2310035O07Rik, A130070J02Rik, B430203M17Rik, Mmac, PTEN, bzs, mham, tep1, mmac1, pten1, Pten |
| Binding Site |
 Alternatives pSer370 |
| Host |
Alternatives Rabbit |
| Reactivity |
Alternatives Human, Mouse (Murine), Rat (Rattus) |
| Conjugate |
Alternatives Un-conjugated |
| Application |
Alternatives Immunohistochemistry (IHC) |
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4 references available |
| Catalog no. | ABIN966918 |
| Quantity | 100ug (100ug/100ul.) (Variants) |
| Price | 385.00 $ Plus shipping costs $45.00 |
| Shipping to |
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| Availability | Will be delivered in 5 to 7 Business Days |
Additional Information
| Alternative name | PTEN |
| Immunogen | The antiserum was produced against synthesized phosphopeptide derived from human PTEN around the phosphorylation site of serine 370 (D-V-SP-D-N). |
| Specificity | PTEN (phospho-Ser370) antibody detects endogenous levels of PTEN only when phosphorylated at serine 370. |
Application Details
| Application Notes |
WB: 1:500~1:1000 IHC: 1:50~1:100. |
| Concentration | 100ug/100ul. |
| Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol |
| Preservative | 0.02% Sodium Azide |
| Storage | Store at -20°C/1 year. |
| Research Area | Cancer, Cell Cycle, Transcription Factors, Kinases/Phosphatases, Signaling |
| Restrictions | For Research Use only |
Publications
| Product |
Vazquez, Ramaswamy, Nakamura et al.: "Phosphorylation of the PTEN tail regulates protein stability and function." in: Molecular and cellular biology, Vol. 20, Issue 14, pp. 5010-8, 2000 (PubMed).
Torres, Pulido: "The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation." in: The Journal of biological chemistry, Vol. 276, Issue 2, pp. 993-8, 2001 (PubMed). Miller, Lou, Seldin et al.: "Direct identification of PTEN phosphorylation sites." in: FEBS letters, Vol. 528, Issue 1-3, pp. 145-53, 2002 (PubMed). Al-Khouri, Ma, Togo et al.: "Cooperative phosphorylation of the tumor suppressor phosphatase and tensin homologue (PTEN) by casein kinases and glycogen synthase kinase 3beta." in: The Journal of biological chemistry, Vol. 280, Issue 42, pp. 35195-202, 2005 (PubMed). |
Alternatives
Alternatives for antigen "Phosphatase and Tensin Homolog (PTEN)", type "Antibodies"
