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PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (pTyr402) antibody

Antigen

PTK2B Protein tyrosine Kinase 2 beta (PTK2B)
Binding Site
Alternatives

pTyr402
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human, Mouse (Murine), Rat (Rattus)
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (IHC)
5 references available
Catalog no. ABIN966926
Quantity 100ug  (100ug/100ul.)
Price 385.00 $   Plus shipping costs $45.00
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Additional Information
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Alternative name Pyk2
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Pyk2 around the phosphorylation site of tyrosine 402 (D-I-YP-A-E).
Specificity Pyk2 (phospho-Tyr402) antibody detects endogenous levels of Pyk2 only when phosphorylated at tyrosine 402.

Application Details
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Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Concentration 100ug/100ul.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using nonphosphopeptide corresponding to the phosphorylation site.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative 0.02% Sodium Azide
Storage Store at -20°C/1 year.
Restrictions For Research Use only

Publications
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Product Lu, Jiang, Blume-Jensen et al.: "Epidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinase." in: Molecular and cellular biology, Vol. 21, Issue 12, pp. 4016-31, 2001 (PubMed).

Benzing, Gerke, Höpker et al.: "Nephrocystin interacts with Pyk2, p130(Cas), and tensin and triggers phosphorylation of Pyk2." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 17, pp. 9784-9, 2001 (PubMed).

Tian, Litvak, Toledo-Rodriguez et al.: "Nir2, a novel regulator of cell morphogenesis." in: Molecular and cellular biology, Vol. 22, Issue 8, pp. 2650-62, 2002 (PubMed).

Gluck: "Acid sensing in renal epithelial cells." in: The Journal of clinical investigation, Vol. 114, Issue 12, pp. 1696-9, 2004 (PubMed).

Krishnan, Sharma-Walia, Streblow et al.: "Focal adhesion kinase is critical for entry of Kaposi's sarcoma-associated herpesvirus into target cells." in: Journal of virology, Vol. 80, Issue 3, pp. 1167-80, 2006 (PubMed).

Alternatives
Application Details Publications back to top

Alternatives for antigen "PTK2B Protein tyrosine Kinase 2 beta (PTK2B)", type "Antibodies"
Hosts Rabbit (92), Mouse (10)
Reactivities Human (95), Rat (Rattus) (58), Mouse (Murine) (56), Cow (Bovine) (7), Dog (Canine) (7), Horse (Equine) (5), Pig (Porcine) (5), Chicken (1)
Applications Western Blotting (WB) (70), ELISA (35), Immunohistochemistry (IHC) (34), Immunofluorescence (IF) (31), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (20), Immunoprecipitation (IP) (10), Immunocytochemistry (ICC) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Functional Studies (Func) (1), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Fluor 350 (3), Alexa Fluor 488 (3), Alexa Fluor 555 (3), Alexa Fluor 647 (3), PE,Cy5.5 (3), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
Epitopes pTyr402 (19), N-Term (7), pTyr881 (6), C-Term (3), AA 991-1009 (2), Tyr402 (2), pTyr579 (2), pTyr580 (2), AA 5-416 (1), AA 681-1009 (1), AA 726-863 (1), AA 815-997 (1), Center (1), Internal Region (1), pSer190 (1), pTyr1135 (1), pTyr579, pTyr580 (1)