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|+1 404 474 4654|
|+1 888 205 9894 (TF)|
PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (pTyr402) antibody
Human, Mouse (Murine), Rat (Rattus)
Alternatives Immunohistochemistry (IHC)
|5 references available|
|Price||385.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 5 to 7 Business Days|
|Immunogen||The antiserum was produced against synthesized phosphopeptide derived from human Pyk2 around the phosphorylation site of tyrosine 402 (D-I-YP-A-E).|
|Specificity||Pyk2 (phospho-Tyr402) antibody detects endogenous levels of Pyk2 only when phosphorylated at tyrosine 402.|
|Purification||The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using nonphosphopeptide corresponding to the phosphorylation site.|
|Buffer||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol|
|Preservative||0.02% Sodium Azide|
|Storage||Store at -20°C/1 year.|
|Restrictions||For Research Use only|
Lu, Jiang, Blume-Jensen et al.: "Epidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinase." in: Molecular and cellular biology, Vol. 21, Issue 12, pp. 4016-31, 2001 (PubMed).
Benzing, Gerke, Höpker et al.: "Nephrocystin interacts with Pyk2, p130(Cas), and tensin and triggers phosphorylation of Pyk2." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 17, pp. 9784-9, 2001 (PubMed).
Tian, Litvak, Toledo-Rodriguez et al.: "Nir2, a novel regulator of cell morphogenesis." in: Molecular and cellular biology, Vol. 22, Issue 8, pp. 2650-62, 2002 (PubMed).
Gluck: "Acid sensing in renal epithelial cells." in: The Journal of clinical investigation, Vol. 114, Issue 12, pp. 1696-9, 2004 (PubMed).
Krishnan, Sharma-Walia, Streblow et al.: "Focal adhesion kinase is critical for entry of Kaposi's sarcoma-associated herpesvirus into target cells." in: Journal of virology, Vol. 80, Issue 3, pp. 1167-80, 2006 (PubMed).