Add to Basket Bulk discount
Order hotline:
+1 404 474 4654
+1 888 205 9894 (TF)

Retinoblastoma 1 (RB1) (pSer795) antibody

Antigen

Retinoblastoma 1 (RB1)
Synonyms RB, pRb, OSRC, pp110, p105-Rb, Rb, Rb-1, RB1, RB11, PP110, P105-RB
Binding Site
Alternatives

pSer795
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human, Mouse (Murine), Rat (Rattus)
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (IHC)
4 references available
Catalog no. ABIN966951
Quantity 100ug  (100ug/100ul.)  (Variants)
Price 385.00 $   Plus shipping costs $45.00
Bulk discount
Shipping to
Availability Will be delivered in 5 to 7 Business Days

Additional Information
Application Details Publications Alternatives Variants back to top

Alternative name Rb
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Rb around the phosphorylation site of serine 795 (P-S-SP-P-L).
Specificity Rb (phospho-Ser795) antibody detects endogenous levels of Rb only when phosphorylated at serine 795 Tested

Application Details
Publications Alternatives Variants back to top

Concentration 100ug/100ul.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative 0.02% Sodium Azide
Storage Store at -20°C/1 year.
Research Area Cancer, Transcription Factors
Restrictions For Research Use only

Publications
Application Details Alternatives Variants back to top

Product Roesch, Becker, Meyer et al.: "Overexpression and hyperphosphorylation of retinoblastoma protein in the progression of malignant melanoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 18, Issue 4, pp. 565-72, 2005 (PubMed).

Leibundgut, Schmitz, Hirt: "Catalytic activities of G1 cyclin-dependent kinases and phosphorylation of retinoblastoma protein in mobilized peripheral blood CD34+ hematopoietic progenitor cells." in: Stem cells (Dayton, Ohio), Vol. 23, Issue 7, pp. 1002-11, 2005 (PubMed).

Wallick, Gamper, Thorne et al.: "Key role for p27Kip1, retinoblastoma protein Rb, and MYCN in polyamine inhibitor-induced G1 cell cycle arrest in MYCN-amplified human neuroblastoma cells." in: Oncogene, Vol. 24, Issue 36, pp. 5606-18, 2005 (PubMed).

Rubin, Gall, Zheng et al.: "Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release." in: Cell, Vol. 123, Issue 6, pp. 1093-106, 2005 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "Retinoblastoma 1 (RB1)", type "Antibodies"
Hosts Rabbit (215), Mouse (68), Rat (1)
Reactivities Human (269), Rat (Rattus) (110), Mouse (Murine) (104), Cow (Bovine) (40), Horse (Equine) (33), Pig (Porcine) (29), Dog (Canine) (17), Chicken (15), Mink (1), Rabbit (1), Zebrafish (1)
Applications Western Blotting (WB) (176), Immunofluorescence (IF) (90), ELISA (76), Immunohistochemistry (IHC) (75), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (62), Immunoprecipitation (IP) (43), Flow Cytometry (FACS) (10), Dot Blot (Dot) (5), Immunocytochemistry (ICC) (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunohistochemistry (Fixed) (IHC (fx)) (2), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Fluor 350 (10), Alexa Fluor 488 (10), Alexa Fluor 555 (10), Alexa Fluor 647 (10), PE,Cy5.5 (10), Biotin (5), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
Epitopes pSer780 (22), pSer795 (17), pSer807 (12), C-Term (9), pSer608 (9), pSer612 (9), pSer788 (8), pSer249 (7), pThr821 (7), pThr826 (7), AA 393-572 (5), pSer811 (5), pSer811,pSer807 (4), Internal Region (3), N-Term (3), Ser780 (3), pThr356 (3), Ser608 (2), Ser795 (2), Ser807 (2), AA 121-140 (1), AA 251-268 (1), AA 280-300 (1), AA 371-390 (1), AA 41-330 (1), AA 511-530 (1), AA 571-590 (1), AA 612-928 (1), AA 800-850 (1), AA 886-905 (1), Center,Ser249 (1), pSer1106 (1), pSer249,pThr252 (1), pSer338 (1), pSer339 (1), pSer807,pSer811 (1), pSer8111 (1), pSer821 (1), pSer826 (1), pThr252,pSer249 (1), pThr373 (1)