Retinoblastoma 1 antibody (RB1)

Details for Product anti-RB1 Antibody No. ABIN966955, Supplier: Log in to see
Antigen
  • RB1
  • OSRC
  • RB
  • p105-Rb
  • pRb
  • pp110
  • Rb
  • Rb-1
  • zgc:154147
  • P105-RB
  • PP110
  • RB11
  • retinoblastoma 1 (including osteosarcoma)
  • retinoblastoma 1
  • Retinoblastoma-associated protein
  • RB1
  • rb
  • Rb1
  • rb1
Alternatives
anti-Human Retinoblastoma 1 antibody for Immunofluorescence (fixed cells)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
594
341
236
10
9
8
8
5
5
4
4
3
3
2
1
1
Host
Rabbit
442
153
1
Clonality
Polyclonal
Conjugate
This Retinoblastoma 1 antibody is un-conjugated
28
26
25
16
14
14
13
13
7
7
7
7
7
7
7
7
7
5
5
5
5
5
5
5
5
3
2
1
1
Application
Immunohistochemistry (IHC)
362
227
160
152
94
82
41
38
26
25
10
9
7
5
5
2
1
1
1
Options
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human Rb around the phosphorylation site of serine 807 (Y-I-SP-P-L).
Specificity Rb (Ab-807) antibody detects endogenous levels of total Rb protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name Rb (RB1 Antibody Abstract)
Pathways Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Roesch, Becker, Meyer, Hafner, Wild, Landthaler, Vogt: "Overexpression and hyperphosphorylation of retinoblastoma protein in the progression of malignant melanoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 18, Issue 4, pp. 565-72, 2005 (PubMed).

Knudsen, Wang: "Dual mechanisms for the inhibition of E2F binding to RB by cyclin-dependent kinase-mediated RB phosphorylation." in: Molecular and cellular biology, Vol. 17, Issue 10, pp. 5771-83, 1997 (PubMed).

Knudsen, Wang: "Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites." in: The Journal of biological chemistry, Vol. 271, Issue 14, pp. 8313-20, 1996 (PubMed).