anti-MAPK9 antibody (Mitogen-Activated Protein Kinase 9) (pThr183)

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Antigen
Synonyms MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK, AI851083, Prkm9, JNK2-ALPHA1, MAP kinase 9
Alternatives
Epitope
pThr183
(23), (15), (15), (14), (12), (10), (10), (7), (7), (6), (6), (6), (5), (5), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(161), (62), (49), (13), (6), (4), (2), (2), (1), (1), (1)
Host
Rabbit
(111), (39), (19), (2), (1)
Conjugate
This MAPK9 antibody is un-conjugated
(5), (4), (3), (3), (3), (3)
Application
Immunohistochemistry (IHC)
(157), (82), (56), (35), (23), (13), (10), (7), (4), (1), (1), (1), (1), (1)
Pubmed 3 references available
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Quantity 100 μg
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human JNK2/3/SAPK around the phosphorylation site of threonine 183 (M-M-TP-P-Y).
Specificity SAPK/JNK (phospho-Thr183) antibody detects endogenous levels of SAPK/JNK only when phosphorylated at threonine 183.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Alternative Name SAPK/JNK (MAPK9 Antibody Abstract)
Pathways MAPK Signaling, WNT Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway
Application Notes IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Matsuyoshi, Shimada, Nakamura et al.: "FADD phosphorylation is critical for cell cycle regulation in breast cancer cells." in: British journal of cancer, Vol. 94, Issue 4, pp. 532-9, 2006 (PubMed).

Ouwens, de Ruiter, van der Zon et al.: "Growth factors can activate ATF2 via a two-step mechanism: phosphorylation of Thr71 through the Ras-MEK-ERK pathway and of Thr69 through RalGDS-Src-p38." in: The EMBO journal, Vol. 21, Issue 14, pp. 3782-93, 2002 (PubMed).

Guan, Buckman, Springer et al.: "Both p38alpha(MAPK) and JNK/SAPK pathways are important for induction of nitric-oxide synthase by interleukin-1beta in rat glomerular mesangial cells." in: The Journal of biological chemistry, Vol. 274, Issue 51, pp. 36200-6, 2000 (PubMed).

Catalog No. ABIN966992
$398.75
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