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SMAD, Mothers Against DPP Homolog 1 (SMAD1) (C-Term) antibody

Details for Product No. ABIN967044
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Antigen
Synonyms
2/23, CG12399, Dmel\\CG12399, E(zen)2, En(vvl), MAD, Mat, P-Mad, P-mad, PMad, Smad, Smad1, apg, c28, dMAD, dMad, l(2)K00237, l(2)k00237, mad, p-Mad, pMAD, pMad, pSmad, fb39h09, madh1, wu:fb39h09, wu:f ... show more
2/23, CG12399, Dmel\\CG12399, E(zen)2, En(vvl), MAD, Mat, P-Mad, P-mad, PMad, Smad, Smad1, apg, c28, dMAD, dMad, l(2)K00237, l(2)k00237, mad, p-Mad, pMAD, pMad, pSmad, fb39h09, madh1, wu:fb39h09, wu:fb97e04, MLP, Xmad1, Xsmad1, smad-1, smad1, xmad, MADH1, BSP-1, BSP1, JV4-1, JV41, MADR1, Madh1, AI528653, Madr1, Mlp1, MusMLP, bsp1, jv4-1, jv41, madr1 show less
Epitope
C-Term
(42), (23), (14), (13), (13), (12), (9), (7), (7), (5), (5), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(237), (148), (134), (42), (26), (21), (18), (5), (4), (4), (4), (4), (4), (4), (3), (2)
Host
Rabbit
(214), (26), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(6), (6), (5), (4), (4), (4), (4), (4), (4), (4), (4), (1), (1), (1)
Application
Western Blotting (WB)
(205), (107), (55), (40), (28), (27), (17), (5), (4), (4), (4), (3), (1), (1), (1), (1)
Pubmed 1 reference available
Quantity 100 µg
Options
Shipping to United States (Change)
Availability Will be delivered in 5 to 7 Business Days
Catalog No. ABIN967044
316.25 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen A synthetic peptide corresponding to a sequence at the C-terminal of human Smad 1,2,3,5, identical to the related mouse and rat sequences.< br/>Immunogen was affinity purified.
Isotype IgG
Cross-Reactivity Mouse (Murine), Rat (Rattus)
Cross-Reactivity (Details) No cross reactivity with other proteins.
Characteristics Rabbit IgG polyclonal antibody for Mothers against decapentaplegic homolog 1 (SMAD1) detection. Tested with WB in Human, Mouse, Rat.
Alternative Name Mothers against decapentaplegic homolog 1(MAD homolog 1/Mothers against DPP homolog 1)
Background SMADs are proteins that modulate the activity of transforming growth factor beta ligands. The SMADs, often in complex with other SMADs/CoSMAD, act as transcription factors that regulate the expression of certain genes. Zhu, H et al concluded that targeted ubiquitination of SMADs may serve to control both embryonic development and a wide variety of cellular responses to TGF-beta signals. R-Smads or receptor regulated Smads are a class of proteins that include SMAD1, SMAD2, SMAD3, SMAD5, and SMAD8. In response to signals by the TGF-beta superfamily of ligands these proteins associate with receptor kinases and are phosphorylated at an SSXS motif at their extreme C-terminus. These proteins then typically bind to the common mediator Smad or co-SMAD SMAD4.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Preservative Sodium azide, Thimerosal (Merthiolate)
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.
Product cited in: Zhu, Kavsak, Abdollah et al.: "A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation." in: Nature, Vol. 400, Issue 6745, pp. 687-93, 1999 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN967044
316.25 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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