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Structural Maintenance of Chromosomes 1A (SMC1A) (pSer957) antibody

Antigen

Structural Maintenance of Chromosomes 1A (SMC1A)
Synonyms SMC1, SMCB, CDLS2, SB1.8, SMC1L1, DXS423E, KIAA0178, MGC138332, SMC1alpha, DKFZp686L19178, SMC-1A, smc1a, smc1l1, zgc:76902, im:7158706, SMC1A, SMC1L2, bK268H5, FLJ43748, SMC1BETA, bK268H5.5, NV15570
Binding Site
Alternatives

pSer957
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human, Mouse (Murine)
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (IHC)
3 references available
Catalog no. ABIN967049
Quantity 100ug  (100ug/100ul.)  (Variants)
Price 385.00 $   Plus shipping costs $45.00
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Additional Information
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Alternative name SMC1
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human SMC1 around the phosphorylation site of serine 957 (G-S-SP-Q-G).
Specificity SMC1 (phospho-Ser957) antibody detects endogenous levels of SMC1 only when phosphorylated at serine 957.

Application Details
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Application Notes WB: 1:500~1:1000.
Concentration 100ug/100ul.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitopespecific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative 0.02% Sodium Azide
Storage Store at -20°C/1 year.
Research Area Chromatin and Nuclear Signaling, Cell Cycle, DNA/RNA
Restrictions For Research Use only

Publications
Application Details Alternatives Variants back to top

Product Revenkova, Eijpe, Heyting et al.: "Novel meiosis-specific isoform of mammalian SMC1." in: Molecular and cellular biology, Vol. 21, Issue 20, pp. 6984-98, 2001 (PubMed).

Kim, Xu, Kastan: "Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage." in: Genes & development, Vol. 16, Issue 5, pp. 560-70, 2002 (PubMed).

Yang, Mehta, Uzri et al.: "Mutations in a partitioning protein and altered chromatin structure at the partitioning locus prevent cohesin recruitment by the Saccharomyces cerevisiae plasmid and cause plasmid missegregation." in: Molecular and cellular biology, Vol. 24, Issue 12, pp. 5290-303, 2004 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "Structural Maintenance of Chromosomes 1A (SMC1A)", type "Antibodies"
Hosts Rabbit (75), Mouse (14), Goat (1), Rat (1)
Reactivities Human (87), Mouse (Murine) (52), Rat (Rattus) (31), Chicken (20), Cow (Bovine) (20), Dog (Canine) (20), Pig (Porcine) (19), Xenopus laevis (1), Zebrafish (1)
Applications Western Blotting (WB) (56), Immunofluorescence (IF) (33), ELISA (22), Immunohistochemistry (IHC) (20), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (16), Immunoprecipitation (IP) (12), Immunocytochemistry (ICC) (5), Flow Cytometry (FACS) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Dot Blot (Dot) (1), Fluorescence Microscopy (FM) (1), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Fluor 350 (3), Alexa Fluor 488 (3), Alexa Fluor 555 (3), Alexa Fluor 647 (3), PE,Cy5.5 (3), Agarose Beads (1), Alexa Flour 488 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
Epitopes pSer957 (19), pSer966 (6), pSer360 (5), N-Term (3), Ser957 (2), AA 916-927 (1), C-Term (1), Internal Region (1), pSer957,AA 951-962 (1), pTyr580 (1)