Structural Maintenance of Chromosomes 1A (SMC1A) (pSer957) antibody

Details for Product No. ABIN967049
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Antigen
Synonyms smc1a, smc1l1, zgc:76902, im:7158706, SMC1L1, SMC1L2, NV15570, CDLS2, DXS423E, SB1.8, SMC1, SMC1alpha, SMCB, 5830426I24Rik, SMC-1A, Sb1.8, Smc1, Smc1alpha, Smc1l1, Smcb, mKIAA0178, smc1aa, smc1, xSMC1
Epitope
pSer957
(48), (14), (14), (12), (8), (7), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(157), (84), (35), (26), (26), (26), (25), (12), (2), (2), (1), (1), (1)
Host
Rabbit
(130), (28), (2), (1), (1)
Conjugate
Un-conjugated
(4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC)
(124), (56), (43), (33), (30), (15), (15), (10), (7), (3), (1)
Pubmed 3 references available
Quantity 100 µg
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Catalog No. ABIN967049
385.00 $
Plus shipping costs $45.00

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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human SMC1 around the phosphorylation site of serine 957 (G-S-SP-Q-G).
Specificity SMC1 (phospho-Ser957) antibody detects endogenous levels of SMC1 only when phosphorylated at serine 957.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitopespecific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Alternative Name SMC1
Research Area Chromatin and Nuclear Signaling, Cell Cycle, DNA/RNA
Application Notes WB: 1:500~1:1000.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Revenkova, Eijpe, Heyting et al.: "Novel meiosis-specific isoform of mammalian SMC1." in: Molecular and cellular biology, Vol. 21, Issue 20, pp. 6984-98, 2001 (PubMed).

Kim, Xu, Kastan: "Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage." in: Genes & development, Vol. 16, Issue 5, pp. 560-70, 2002 (PubMed).

Yang, Mehta, Uzri et al.: "Mutations in a partitioning protein and altered chromatin structure at the partitioning locus prevent cohesin recruitment by the Saccharomyces cerevisiae plasmid and cause plasmid missegregation." in: Molecular and cellular biology, Vol. 24, Issue 12, pp. 5290-303, 2004 (PubMed).

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