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|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Structural Maintenance of Chromosomes 1A (SMC1A) (pSer957) antibody
|Synonyms||SMC1, SMCB, CDLS2, SB1.8, SMC1L1, DXS423E, KIAA0178, MGC138332, SMC1alpha, DKFZp686L19178, SMC-1A, smc1a, smc1l1, zgc:76902, im:7158706, SMC1A, SMC1L2, bK268H5, FLJ43748, SMC1BETA, bK268H5.5, NV15570|
Human, Mouse (Murine)
Alternatives Immunohistochemistry (IHC)
|3 references available|
|Quantity||100ug (100ug/100ul.) (Variants)|
|Price||385.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 5 to 7 Business Days|
|Immunogen||The antiserum was produced against synthesized phosphopeptide derived from human SMC1 around the phosphorylation site of serine 957 (G-S-SP-Q-G).|
|Specificity||SMC1 (phospho-Ser957) antibody detects endogenous levels of SMC1 only when phosphorylated at serine 957.|
|Application Notes||WB: 1:500~1:1000.|
|Purification||The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitopespecific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.|
|Buffer||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol|
|Preservative||0.02% Sodium Azide|
|Storage||Store at -20°C/1 year.|
|Research Area||Chromatin and Nuclear Signaling, Cell Cycle, DNA/RNA|
|Restrictions||For Research Use only|
Revenkova, Eijpe, Heyting et al.: "Novel meiosis-specific isoform of mammalian SMC1." in: Molecular and cellular biology, Vol. 21, Issue 20, pp. 6984-98, 2001 (PubMed).
Kim, Xu, Kastan: "Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage." in: Genes & development, Vol. 16, Issue 5, pp. 560-70, 2002 (PubMed).
Yang, Mehta, Uzri et al.: "Mutations in a partitioning protein and altered chromatin structure at the partitioning locus prevent cohesin recruitment by the Saccharomyces cerevisiae plasmid and cause plasmid missegregation." in: Molecular and cellular biology, Vol. 24, Issue 12, pp. 5290-303, 2004 (PubMed).