SRC antibody (V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian)) (pTyr529)

Details for Product anti-SRC Antibody No. ABIN967080, Supplier: Log in to see
Antigen
  • AW259666
  • pp60c-src
  • C-src1
  • CG7524
  • D-Src64B
  • D-src
  • DSRC64
  • DSrc
  • DSrc64
  • DSrc64B
  • Dm SRC1
  • DmHD-358
  • Dmel\CG7524
  • Dsrc
  • Dsrc64
  • Dsrc64B
  • HD-358
  • MRE5
  • SRC 64B
  • Src
  • Src1
  • Src64
  • c-src
  • dSrc
  • dsrc
  • src
  • src1
  • src64
  • src64B
  • src64b
  • ASV
  • SRC1
  • c-SRC
  • p60-Src
  • c-Src
  • PP60C-SCR
  • SDR
  • v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • proto-oncogene tyrosine-protein kinase src
  • Rous sarcoma oncogene
  • Src oncogene at 64B
  • v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
  • v-src sarcoma viral oncogene
  • SRC
  • AaeL_AAEL002471
  • CpipJ_CPIJ010659
  • Src
  • Src64B
Alternatives
anti-Human SRC antibody for Immunofluorescence (fixed cells)
Epitope
pTyr529
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31
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27
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24
20
15
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11
8
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1
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1
1
1
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1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
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243
197
30
17
16
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11
9
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5
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4
4
2
1
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Host
Rabbit
365
71
1
1
Conjugate
This SRC antibody is un-conjugated
19
19
15
14
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13
3
3
2
2
2
2
2
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2
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2
Application
Immunohistochemistry (IHC)
366
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143
50
39
32
27
20
12
9
5
5
3
3
1
Options
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Src around the phosphorylation site of tyrosine 529 (P-Q-YP-Q-P).
Specificity Src (phospho-Tyr529) antibody detects endogenous levels of Src only when phosphorylated at tyrosine 529.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Alternative Name Src (SRC Antibody Abstract)
Research Area Cancer, Transcription Factors, Tyrosine Kinases, Signaling
Pathways JAK-STAT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Benes, Wu, Elia, Dharia, Cantley, Soltoff: "The C2 domain of PKCdelta is a phosphotyrosine binding domain." in: Cell, Vol. 121, Issue 2, pp. 271-80, 2005 (PubMed).

Xu, Harrison, Eck: "Three-dimensional structure of the tyrosine kinase c-Src." in: Nature, Vol. 385, Issue 6617, pp. 595-602, 1997 (PubMed).

Pyper, Bolen: "Identification of a novel neuronal C-SRC exon expressed in human brain." in: Molecular and cellular biology, Vol. 10, Issue 5, pp. 2035-40, 1990 (PubMed).

Parker, Mardon, Lebo, Varmus, Bishop: "Isolation of duplicated human c-src genes located on chromosomes 1 and 20." in: Molecular and cellular biology, Vol. 5, Issue 4, pp. 831-8, 1985 (PubMed).