HSC70 Interacting Protein HIP antibody

Catalog No. ABIN967083

Product Details anti-HSC70 Interacting Protein HIP Antibody

Target: HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))

Reactivity: Human, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This HSC70 Interacting Protein HIP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human ST13 expressed in E. Coli.

Clone: 3B10

Isotype: IgG1

Application Details

Application Notes: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-HSC70 Interacting Protein HIP antibody (ABIN967083)

Velten, Gomez-Vrielynck, Chaffotte, Ladjimi: "Domain structure of the HSC70 cochaperone, HIP." in: The Journal of biological chemistry, Vol. 277, Issue 1, pp. 259-66, (2002) (PubMed).

Target Details for HSC70 Interacting Protein HIP

Target: HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))

Alternative Name: ST13 (ST13 Products)

Synonyms: CG32789 antibody, Dmel\\CG32789 antibody, anon-EST:fe1A9 antibody, 1110007I03Rik antibody, 3110002K08Rik antibody, AW555194 antibody, HIP antibody, HOP antibody, HSPABP antibody, HSPABP1 antibody, PRO0786 antibody, SNC6 antibody, p48 antibody, AAG2 antibody, FAM10A1 antibody, FAM10A4 antibody, P48 antibody, Hsc/Hsp70-interacting protein antibody, suppression of tumorigenicity 13 antibody, ST13, Hsp70 interacting protein antibody, suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) antibody, HIP antibody, St13 antibody, ST13 antibody

Background: ST13 (suppression of tumorigenicity protein 13), also known as Hip (HSP70-interacting protein), is one of several cochaperones that regulate activities of the HSP70 chaperone family. The homo-oligomeric protein Hip cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70. Hip directly binds to the ATPase domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 family. By collaborating with other positive co-factors such as HSP40 and Hop, or competing with negative co-factors such as Bag1, Hip may facilitate the chaperone function of HSP70 in protein folding and repair, and in controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis.
Synonyms: HIP, HOP, P48, AAG2, SNC6, HSPABP, FAM10A1, FAM10A4, HSPABP1, ST13

Molecular Weight: 48kDa

Gene ID: 6767