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STAT1 antibody (Signal Transducer and Activator of Transcription 1, 91kDa) (pTyr701)

Details for Product anti-STAT1 Antibody No. ABIN967085, Supplier: Log in to see
Antigen
  • IMUP
  • H2RSP
  • IMUP-1
  • IMUP-2
  • 2010005J02Rik
  • AA408197
  • DD6G4-4
  • CANDF7
  • ISGF-3
  • STAT91
  • STAT4
  • XStat1
  • STAT
  • STAT1
  • dZ182H3.3
  • si:by134g18.2
  • si:by51f19.1
  • si:dz182h3.3
  • si:dz199m19.1
  • si:dz73o4.2
Alternatives
anti-Human STAT1 antibody for Immunoprecipitation
Epitope
pTyr701
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69
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Reactivity
Human, Mouse (Murine), Rat (Rattus)
427
211
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Host
Rabbit
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Conjugate
This STAT1 antibody is un-conjugated
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Application
Immunohistochemistry (IHC)
370
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45
33
18
18
10
9
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2
2
1
Supplier
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human STAT1 around the phosphorylation site of tyrosine 701 (T-G-YP-I-K).
Specificity STAT1 (phospho-Tyr701) antibody detects endogenous levels of STAT1 only when phosphorylated at tyrosine 701.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Alternative Name STAT1 (STAT1 Antibody Abstract)
Research Area Cancer, Transcription Factors, Signaling, Receptors, Inflammation
Pathways JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Demoulin, Van Roost, Stevens et al.: "Distinct roles for STAT1, STAT3, and STAT5 in differentiation gene induction and apoptosis inhibition by interleukin-9." in: The Journal of biological chemistry, Vol. 274, Issue 36, pp. 25855-61, 1999 (PubMed).

Background publications Heim: "The Jak-STAT pathway: cytokine signalling from the receptor to the nucleus." in: Journal of receptor and signal transduction research, Vol. 19, Issue 1-4, pp. 75-120, 1999 (PubMed).

Durbin, Hackenmiller, Simon et al.: "Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease." in: Cell, Vol. 84, Issue 3, pp. 443-50, 1996 (PubMed).

Ihle, Witthuhn, Quelle et al.: "Signaling by the cytokine receptor superfamily: JAKs and STATs." in: Trends in biochemical sciences, Vol. 19, Issue 5, pp. 222-7, 1994 (PubMed).