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STAT3 antibody (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor)) (pSer727)

Details for Product anti-STAT3 Antibody No. ABIN967089, Supplier: Log in to see
Antigen
  • 1110034C02Rik
  • AW109958
  • Aprf
  • APRF
  • HIES
  • Xstat3
  • aprf
  • hies
  • stat3
  • wu:fc15d02
  • wu:fl59g06
  • z-Stat3
Alternatives
anti-Human STAT3 antibody for Western Blotting
Epitope
pSer727
107
94
83
28
21
17
16
15
14
13
13
8
6
5
5
5
5
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4
3
3
3
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3
3
3
3
2
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2
2
2
2
2
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2
2
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2
1
1
1
1
1
1
1
1
1
1
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1
1
1
1
1
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1
1
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1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
524
253
197
31
24
24
13
11
10
5
5
4
3
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2
2
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Host
Rabbit
454
100
34
4
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1
Conjugate
This STAT3 antibody is un-conjugated
24
22
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11
7
4
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Application
Immunohistochemistry (IHC)
489
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24
13
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12
9
7
3
3
2
2
2
1
1
1
1
1
Supplier
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human STAT3 around the phosphorylation site of serine 727 (P-M-SP-P-R).
Specificity STAT3 (phospho-Ser727) antibody detects endogenous levels of STAT3 only when phosphorylated at serine 727.
Alternative Name STAT3 (STAT3 Antibody Abstract)
Research Area Embryogenesis, Embryonic stem cells, Transcription Factors, Signaling, Receptors, Inflammation
Pathways JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Neurotrophin Signaling Pathway
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Background publications Heim: "The Jak-STAT pathway: cytokine signalling from the receptor to the nucleus." in: Journal of receptor and signal transduction research, Vol. 19, Issue 1-4, pp. 75-120, 1999 (PubMed).

Catlett-Falcone, Landowski, Oshiro et al.: "Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells." in: Immunity, Vol. 10, Issue 1, pp. 105-15, 1999 (PubMed).

Takeda, Noguchi, Shi et al.: "Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 8, pp. 3801-4, 1997 (PubMed).