anti-STAT3 antibody (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor)) (pTyr705)

Details for Product anti-STAT3 Antibody No. ABIN967090
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Antigen
Synonyms 1110034C02Rik, AW109958, Aprf, APRF, HIES, Xstat3, aprf, hies, stat3, wu:fc15d02, wu:fl59g06, z-Stat3
Epitope
pTyr705
(96), (87), (75), (23), (16), (15), (14), (13), (12), (12), (11), (9), (8), (7), (6), (5), (5), (5), (5), (5), (5), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(515), (227), (176), (20), (14), (13), (11), (8), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1)
Host
Rabbit
(471), (85), (36), (4), (2), (1)
Conjugate
This STAT3 antibody is un-conjugated
(29), (23), (17), (14), (12), (12), (6), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC)
(510), (241), (231), (87), (80), (79), (56), (32), (21), (18), (16), (14), (12), (8), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1)
Pubmed 5 references available
Quantity 100 μg
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Request Want additional data for this product?

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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human STAT3 around the phosphorylation site of tyrosine 705 (A-P-YP-L-K).
Specificity STAT3 (phospho-Tyr705) antibody detects endogenous levels of STAT3 only when phosphorylated at tyrosine 705.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Alternative Name STAT3 (STAT3 Antibody Abstract)
Research Area Embryogenesis, Embryonic stem cells, Transcription Factors, Signaling, Receptors, Inflammation
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Welsh, Wilson, Proud: "GSK3: a SHAGGY frog story." in: Trends in cell biology, Vol. 6, Issue 7, pp. 274-9, 2004 (PubMed).

Fan, Ballou, Lin: "Phospholipase C-independent activation of glycogen synthase kinase-3beta and C-terminal Src kinase by Galphaq." in: The Journal of biological chemistry, Vol. 278, Issue 52, pp. 52432-6, 2003 (PubMed).

Barry, Graham, Fry et al.: "Regulation of glycogen synthase kinase 3 in human platelets: a possible role in platelet function?" in: FEBS letters, Vol. 553, Issue 1-2, pp. 173-8, 2003 (PubMed).

Leadbetter: "Cultivation of recalcitrant microbes: cells are alive, well and revealing their secrets in the 21st century laboratory." in: Current opinion in microbiology, Vol. 6, Issue 3, pp. 274-81, 2003 (PubMed).

Srivastava, Pandey: "Potential mechanism(s) involved in the regulation of glycogen synthesis by insulin." in: Molecular and cellular biochemistry, Vol. 182, Issue 1-2, pp. 135-41, 1999 (PubMed).

Validation Images
Catalog No. ABIN967090
398.75 $
Plus shipping costs $45.00
Quantity
Price
100 μg
398.75 $

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