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STAT3 antibody (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor))

Details for Product anti-STAT3 Antibody No. ABIN967092, Supplier: Login to see
Antigen
  • 1110034C02Rik
  • AW109958
  • Aprf
  • APRF
  • HIES
  • Xstat3
  • aprf
  • hies
  • stat3
  • wu:fc15d02
  • wu:fl59g06
  • z-Stat3
Alternatives
anti-Human STAT3 antibody for Western Blotting
Reactivity
Human, Mouse (Murine), Rat (Rattus)
544
255
197
31
24
24
13
11
10
5
5
4
3
2
2
2
2
1
1
1
1
Host
Rabbit
470
103
36
4
2
1
Clonality
Polyclonal
Conjugate
This STAT3 antibody is un-conjugated
24
22
18
13
12
11
7
4
3
2
2
2
2
2
2
1
1
1
1
1
1
Application
Immunohistochemistry (IHC)
509
240
220
85
77
77
56
25
24
13
13
12
9
7
3
3
2
2
2
1
1
1
1
1
Supplier
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human STAT3 around the phosphorylation site of serine 727 (P-M-SP-P-R).
Specificity STAT3 (Ab-727) antibody detects endogenous levels of total STAT3 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name STAT3 (STAT3 Antibody Abstract)
Pathways JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Neurotrophin Signaling Pathway
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Heim: "The Jak-STAT pathway: cytokine signalling from the receptor to the nucleus." in: Journal of receptor and signal transduction research, Vol. 19, Issue 1-4, pp. 75-120, 1999 (PubMed).

Catlett-Falcone, Landowski, Oshiro et al.: "Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells." in: Immunity, Vol. 10, Issue 1, pp. 105-15, 1999 (PubMed).

Garcia, Jove: "Activation of STAT transcription factors in oncogenic tyrosine kinase signaling." in: Journal of biomedical science, Vol. 5, Issue 2, pp. 79-85, 1998 (PubMed).

Takeda, Noguchi, Shi et al.: "Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 8, pp. 3801-4, 1997 (PubMed).

Background publications Bromberg, Wrzeszczynska, Devgan et al.: "Stat3 as an oncogene." in: Cell, Vol. 98, Issue 3, pp. 295-303, 1999 (PubMed).