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Details for Product No. ABIN967092

Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) antibody

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Antigen
Synonyms APRF, HIES, wu:fc15d02, wu:fl59g06, z-Stat3, Aprf, AW109958, 1110034C02Rik, STAT3
Reactivity
»Alternatives Human, Mouse (Murine), Rat (Rattus)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC)
Pubmed 5 references available
Catalog no. ABIN967092
Quantity 100 µg
Price
385.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 5 to 7 Business Days
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human STAT3 around the phosphorylation site of serine 727 (P-M-SP-P-R).
Specificity STAT3 (Ab-727) antibody detects endogenous levels of total STAT3 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name STAT3
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Storage -20 °C
Product cited in: Takeda, Noguchi, Shi et al.: "Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 8, pp. 3801-4, 1997 (PubMed).

Garcia, Jove: "Activation of STAT transcription factors in oncogenic tyrosine kinase signaling." in: Journal of biomedical science, Vol. 5, Issue 2, pp. 79-85, 1998 (PubMed).

Catlett-Falcone, Landowski, Oshiro et al.: "Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells." in: Immunity, Vol. 10, Issue 1, pp. 105-15, 1999 (PubMed).

Heim: "The Jak-STAT pathway: cytokine signalling from the receptor to the nucleus." in: Journal of receptor and signal transduction research, Vol. 19, Issue 1-4, pp. 75-120, 1999 (PubMed).

Bromberg, Wrzeszczynska, Devgan et al.: "Stat3 as an oncogene." in: Cell, Vol. 98, Issue 3, pp. 295-303, 1999 (PubMed).

Alternatives for antigen "Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3)", type "Antibodies"
Hosts (276), (48), (15), (1), (1)
Reactivities (307), (187), (160), (49), (48), (40), (39), (36), (7), (7), (4), (2), (1), (1), (1), (1)
Applications (285), (129), (102), (79), (60), (49), (43), (30), (14), (10), (8), (5), (3), (3), (2), (1), (1), (1), (1)
Conjugates (11), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (1), (1), (1), (1)
Epitopes (62), (51), (28), (10), (9), (6), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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