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STAT5A antibody (Signal Transducer and Activator of Transcription 5A) (pSer780)

Details for Product anti-STAT5A Antibody No. ABIN967095, Supplier: Login to see
Antigen
  • STAT5A
  • STAT5
  • MGF
  • AA959963
  • Stat5
  • STAT5A/MGF
  • STATA5
Alternatives
anti-Human STAT5A antibody for Immunohistochemistry (Frozen Sections)
Epitope
pSer780
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42
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5
5
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3
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1
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1
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1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
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28
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6
1
1
Host
Rabbit
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99
10
Conjugate
This STAT5A antibody is un-conjugated
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Application
Immunohistochemistry (IHC)
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9
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2
2
1
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Supplier
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human STAT5A around the phosphorylation site of serine 780 (R-L-SP-P-P).
Specificity STAT5A (phospho-Ser780) antibody detects endogenous levels of STAT5A only when phosphorylated at serine 780.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Alternative Name STAT5A (STAT5A Antibody Abstract)
Pathways JAK-STAT Signaling, RTK Signaling
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Gouilleux, Wakao, Mundt et al.: "Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription." in: The EMBO journal, Vol. 13, Issue 18, pp. 4361-9, 1994 (PubMed).

Background publications Dentelli, Del Sorbo, Rosso et al.: "Human IL-3 stimulates endothelial cell motility and promotes in vivo new vessel formation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 4, pp. 2151-9, 1999 (PubMed).

Meinke, Barahmand-Pour, Wöhrl et al.: "Activation of different Stat5 isoforms contributes to cell-type-restricted signaling in response to interferons." in: Molecular and cellular biology, Vol. 16, Issue 12, pp. 6937-44, 1997 (PubMed).