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Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (pTyr641) antibody

Antigen

Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6)
Synonyms STAT6B, STAT6C, D12S1644, IL-4-STAT
Binding Site
Alternatives

pTyr641
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (IHC)
4 references available
Catalog no. ABIN967101
Quantity 100ug  (100ug/100ul.)  (Variants)
Price 385.00 $   Plus shipping costs $45.00
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Alternative name STAT6
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human STAT6 around the phosphorylation site of Tyrosine 641 (R-G-YP-V-P).
Specificity STAT6 (phospho-Tyr641) antibody detects endogenous levels of STAT6 only when phosphorylated at tyrosine 641.

Application Details
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Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Concentration 100ug/100ul.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative 0.02% Sodium Azide
Storage Store at -20°C/1 year.
Research Area Chromatin and Nuclear Signaling, Receptors, Inflammation
Restrictions For Research Use only

Publications
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Product Quelle, Shimoda, Thierfelder et al.: "Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis." in: Molecular and cellular biology, Vol. 15, Issue 6, pp. 3336-43, 1995 (PubMed).

Hou, Schindler, Henzel et al.: "An interleukin-4-induced transcription factor: IL-4 Stat." in: Science (New York, N.Y.), Vol. 265, Issue 5179, pp. 1701-6, 1994 (PubMed).

Malabarba, Rui, Deutsch et al.: "Interleukin-13 is a potent activator of JAK3 and STAT6 in cells expressing interleukin-2 receptor-gamma and interleukin-4 receptor-alpha." in: The Biochemical journal, Vol. 319 ( Pt 3), pp. 865-72, 1996 (PubMed).

Nelms, Keegan, Zamorano et al.: "The IL-4 receptor: signaling mechanisms and biologic functions." in: Annual review of immunology, Vol. 17, pp. 701-38, 1999 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6)", type "Antibodies"
Hosts Rabbit (129), Mouse (28), Chicken (2)
Reactivities Human (151), Rat (Rattus) (50), Mouse (Murine) (47), Pig (Porcine) (7), Cow (Bovine) (5), Horse (Equine) (5), Dog (Canine) (3), Monkey (3)
Applications Western Blotting (WB) (115), ELISA (48), Immunohistochemistry (IHC) (44), Immunofluorescence (IF) (32), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (28), Immunoprecipitation (IP) (25), Flow Cytometry (FACS) (9), Immunocytochemistry (ICC) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Fluorescence Microscopy (FM) (2), Immunoassay (IA) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1)
Conjugates Alexa Fluor 350 (3), Alexa Fluor 488 (3), Alexa Fluor 555 (3), Alexa Fluor 647 (3), PE,Cy5.5 (3), PE (2), APC (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
Epitopes pTyr641 (23), pThr645 (15), C-Term (11), AA 808-826 (4), Tyr641 (4), AA 630-650 (3), AA 342-640 (2), AA 806-826 (2), Internal Region (2), Thr645 (2), pTyr641,Internal Region (2), AA 61-275 (1), AA 620 (1), N-Term (1), Phosphospecific (1), pThr641 (1), pTyr642 (1), pTyr694 (1), phospho (1)