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Oligonucleotide/oligosaccharide-Binding Fold Containing 1 (OBFC1) (N-Term) antibody

Details for Product No. ABIN967111, Supplier: Log in to see
Antigen
  • AAF-44
  • AAF44
  • RP11-541N10.2
  • RPA-32
  • STN1
  • bA541N10.2
  • 0610009H20Rik
  • 2310057J23Rik
  • AI413458
  • zgc:64174
  • ATSTN1
  • F10K1.17
  • F10K1_17
Epitope
N-Term
19
16
6
4
2
2
1
1
Reactivity
Yeast (Saccharomyces cerevisiae)
36
1
Host
Rabbit
25
12
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Immunohistochemistry (IHC)
33
17
6
5
2
1
Supplier
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Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to near N-terminal residues of Baker's Yeast (Saccharomyces cerevisiae) STN1 (Protein STN1)
Alternative Name STN1 (OBFC1 Antibody Abstract)
Background STN1 (Protein STN1) has a role in telomere length regulation and telomere end protection. Acts as an inhibitor of telomerase loading through its interaction with CDC13. STN1 (Protein STN1)interacts with CDC13 and TEN1. STN1 may localize in Telomere and it is similar to YDR082W STN1 Telomere end-binding and capping protein, plays a key role with Pol12p in linking telomerase action with completion of lagging strand synthesis, and in a regulatory step required for telomere capping.
Synonyms: D4456, YD8554.15
Restrictions For Research Use only
Product cited in: Albuquerque, Smolka, Payne et al.: "A multidimensional chromatography technology for in-depth phosphoproteome analysis." in: Molecular & cellular proteomics : MCP, Vol. 7, Issue 7, pp. 1389-96, 2008 (PubMed).

Chandra, Hughes, Nugent et al.: "Cdc13 both positively and negatively regulates telomere replication." in: Genes & development, Vol. 15, Issue 4, pp. 404-14, 2001 (PubMed).

Grandin, Damon, Charbonneau: "Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13." in: The EMBO journal, Vol. 20, Issue 5, pp. 1173-83, 2001 (PubMed).

Grandin, Reed, Charbonneau: "Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13." in: Genes & development, Vol. 11, Issue 4, pp. 512-27, 1997 (PubMed).

Coster, Jonniaux, Goffeau: "Analysis of a 32.8 kb segment of yeast chromosome IV reveals 21 open reading frames, including TPS2, PPH3, RAD55, SED1, PDC2, AFR1, SSS1, SLU7 and a tRNA for arginine." in: Yeast (Chichester, England), Vol. 11, Issue 7, pp. 673-9, 1995 (PubMed).