STN1 (N-Term,pThr223) antibody

Antigen: STN1

Binding Site: N-Term,pThr223

Clonality: Polyclonal

Host: Please enquire

Reactivity: Yeast (Saccharomyces cerevisiae)

Application: Please enquire

Catalog no.: ABIN967112

Additional Information

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to near N-terminal residues of Baker's Yeast (Saccharomyces cerevisiae) STN1 (Protein STN1)

Description: STN1 (Protein STN1) has a role in telomere length regulation and telomere end protection. Acts as an inhibitor of telomerase loading through its interaction with CDC13. STN1 (Protein STN1)interacts with CDC13 and TEN1. STN1 may localize in Telomere and it is similar to YDR082W STN1 Telomere end-binding and capping protein, plays a key role with Pol12p in linking telomerase action with completion of lagging strand synthesis, and in a regulatory step required for telomere capping.
Synonyms: D4456, YD8554.15

Application Details

Restrictions: For Research Use only

Publications

Product: Coster, Jonniaux, Goffeau: "Analysis of a 32.8 kb segment of yeast chromosome IV reveals 21 open reading frames, including TPS2, PPH3, RAD55, SED1, PDC2, AFR1, SSS1, SLU7 and a tRNA for arginine." in: Yeast (Chichester, England), Vol. 11, Issue 7, pp. 673-9, 1995 (PubMed).

Grandin, Reed, Charbonneau: "Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13." in: Genes & development, Vol. 11, Issue 4, pp. 512-27, 1997 (PubMed).

Grandin, Damon, Charbonneau: "Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13." in: The EMBO journal, Vol. 20, Issue 5, pp. 1173-83, 2001 (PubMed).

Chandra, Hughes, Nugent et al.: "Cdc13 both positively and negatively regulates telomere replication." in: Genes & development, Vol. 15, Issue 4, pp. 404-14, 2001 (PubMed).

Albuquerque, Smolka, Payne et al.: "A multidimensional chromatography technology for in-depth phosphoproteome analysis." in: Molecular & cellular proteomics : MCP, Vol. 7, Issue 7, pp. 1389-96, 2008 (PubMed).