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Solute Carrier Family 18 (Vesicular Monoamine Transporter), Member 2 (SLC18A2) (C-Term) antibody

Details for Product No. ABIN967117, Supplier: Log in to see
Antigen
Epitope
C-Term
24
2
2
2
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
44
23
16
4
3
2
1
Host
Rabbit
36
13
7
3
2
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
1
1
1
Application
Immunohistochemistry (IHC)
47
29
20
7
4
3
3
2
1
1
Supplier
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Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human SVMT(Synaptic vesicular amine transporter)
Alternative Name SVMT
Background SVMT(Synaptic vesicular amine transporter) is involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. SVMT is requisite for vesicular amine storage prior to secretion via exocytosis. SVMT belongs to the major facilitator superfamily and vesicular transporter family.
Restrictions For Research Use only
Background publications Zahedi, Lewandrowski, Wiesner, Wortelkamp, Moebius, Schütz, Walter, Gambaryan, Sickmann: "Phosphoproteome of resting human platelets." in: Journal of proteome research, Vol. 7, Issue 2, pp. 526-34, 2008

Product cited in: Thiriot, Sievert, Ruoho: "Identification of human vesicle monoamine transporter (VMAT2) lumenal cysteines that form an intramolecular disulfide bond." in: Biochemistry, Vol. 41, Issue 20, pp. 6346-53, 2002

Peter, Finn, Klisak, Liu, Kojis, Heinzmann, Roghani, Sparkes, Edwards: "Chromosomal localization of the human vesicular amine transporter genes." in: Genomics, Vol. 18, Issue 3, pp. 720-3, 1994

Surratt, Persico, Yang, Edgar, Bird, Hawkins, Griffin, Li, Jabs, Uhl: "A human synaptic vesicle monoamine transporter cDNA predicts posttranslational modifications, reveals chromosome 10 gene localization and identifies TaqI RFLPs." in: FEBS letters, Vol. 318, Issue 3, pp. 325-30, 1993

Erickson, Eiden: "Functional identification and molecular cloning of a human brain vesicle monoamine transporter." in: Journal of neurochemistry, Vol. 61, Issue 6, pp. 2314-7, 1993

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