TAF2 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 150kDa (TAF2) (N-Term,Middle Region) antibody

Antigen: TAF2 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 150kDa (TAF2)

Binding Site: N-Term,Middle Region

Clonality: Polyclonal

Host: Rabbit

Reactivity: Yeast (Saccharomyces cerevisiae)

Application: Immunohistochemistry (IHC)

Catalog no.: ABIN967134

Additional Information

Alternative name: TAF2

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to Nterminal-middle residues of Saccharomyces cerevisiae (baker's yeast) TAF2(TBP-associated factor 2), (Transcription initiation factor TFIID subunit 2)

Description: TAF2(TBP-associated factor 2) functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter(with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription. The 1.2 MDa TFIID complex is composed of TATA binding protein (TBP) and the 14 TBP-associated factors.
Synonyms: TAF150(TBP-associated factor 150), TSM1, YCR42C, YCR724

Application Details

Restrictions: For Research Use only

Publications

Product: Jacquet, Buhler, Iborra et al.: "The MAT locus revisited within a 9.8 kb fragment of chromosome III containing BUD5 and two new open reading frames." in: Yeast (Chichester, England), Vol. 7, Issue 8, pp. 881-8, 1992 (PubMed).

Ray, White, Haber: "The TSM1 gene of Saccharomyces cerevisiae overlaps the MAT locus." in: Current genetics, Vol. 20, Issue 1-2, pp. 25-31, 1991 (PubMed).

Poon, Bai, Campbell et al.: "Identification and characterization of a TFIID-like multiprotein complex from Saccharomyces cerevisiae." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 18, pp. 8224-8, 1995 (PubMed).

Sanders, Weil: "Identification of two novel TAF subunits of the yeast Saccharomyces cerevisiae TFIID complex." in: The Journal of biological chemistry, Vol. 275, Issue 18, pp. 13895-900, 2000 (PubMed).

Leurent, Sanders, Ruhlmann et al.: "Mapping histone fold TAFs within yeast TFIID." in: The EMBO journal, Vol. 21, Issue 13, pp. 3424-33, 2002 (PubMed).

Sanders, Garbett, Weil: "Molecular characterization of Saccharomyces cerevisiae TFIID." in: Molecular and cellular biology, Vol. 22, Issue 16, pp. 6000-13, 2002 (PubMed).

Martinez: "Multi-protein complexes in eukaryotic gene transcription." in: Plant molecular biology, Vol. 50, Issue 6, pp. 925-47, 2003 (PubMed).

Ghaemmaghami, Huh, Bower et al.: "Global analysis of protein expression in yeast." in: Nature, Vol. 425, Issue 6959, pp. 737-41, 2003 (PubMed).