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Microtubule-Associated Protein tau (MAPT) (pSer396) antibody

Antigen

Microtubule-Associated Protein tau (MAPT)
Synonyms TAU, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, FTDP-17, FLJ31424, MGC138549, Tau, Mtapt, AI413597, AW045860, pTau, RNPTAU, MGC156663, tau, MGC134287, xtp, MAPT
Binding Site
Alternatives

pSer396
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human, Mouse (Murine), Rat (Rattus)
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (IHC)
4 references available
Catalog no. ABIN967146
Quantity 100ug  (100ug/100ul.)  (Variants)
Price 385.00 $   Plus shipping costs $45.00
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Alternative name Tau
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Tau around the phosphorylation site of serine 396 (Y-K-SP-P-V).
Specificity Tau (phospho-Ser396) antibody detects endogenous levels of Tau only when phosphorylated at serine396.

Application Details
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Application Notes WB: 1:500~1:1000.
Concentration 100ug/100ul.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative 0.02% Sodium Azide
Storage Store at -20°C/1 year.
Research Area Neurology, Cytoskeleton, Alzheimer's Disease
Restrictions For Research Use only

Publications
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Product Kyriakis, Banerjee, Nikolakaki et al.: "The stress-activated protein kinase subfamily of c-Jun kinases." in: Nature, Vol. 369, Issue 6476, pp. 156-60, 1994 (PubMed).

Alonso, Mederlyova, Novak et al.: "Promotion of hyperphosphorylation by frontotemporal dementia tau mutations." in: The Journal of biological chemistry, Vol. 279, Issue 33, pp. 34873-81, 2004 (PubMed).

DeGiorgis, Jaffe, Moreira et al.: "Phosphoproteomic analysis of synaptosomes from human cerebral cortex." in: Journal of proteome research, Vol. 4, Issue 2, pp. 306-15, 2005 (PubMed).

Puig, Rey, Ferrer: "Individual and regional variations of phospho-tau species in progressive supranuclear palsy." in: Acta neuropathologica, Vol. 110, Issue 3, pp. 261-8, 2005 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "Microtubule-Associated Protein tau (MAPT)", type "Antibodies"
Hosts Rabbit (261), Mouse (51), Goat (6), Chicken (3)
Reactivities Human (291), Rat (Rattus) (168), Mouse (Murine) (144), Cow (Bovine) (21), Chicken (2), Cat (Feline) (1), Dog (Canine) (1), Sheep (Ovine) (1)
Applications Western Blotting (WB) (278), ELISA (96), Immunohistochemistry (IHC) (78), Immunofluorescence (IF) (32), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (28), Immunoprecipitation (IP) (21), Dot Blot (Dot) (14), Cellular Assay (CA) (13), Immunoassay (IA) (13), Immunostaining (ISt) (13), Enzyme Immunoassay (EIA) (9), Immunocytochemistry (ICC) (8), Immunohistochemistry (Fixed) (IHC (fx)) (3), Flow Cytometry (FACS) (2), To be determined by user (TBD) (1)
Conjugates Biotin (5), FITC (1)
Epitopes pThr231 (12), pSer262 (11), Internal Region (10), pSer396 (10), pThr205 (10), pSer214 (9), pSer235 (9), pSer356 (9), pSer404 (9), pThr181 (9), pThr212 (8), C-Term (7), pSer422 (6), N-Term (4), Ser262 (4), Ser356 (4), Ser404 (4), Ser422 (4), Thr181 (4), pSer199 (4), Ser214 (3), Ser235 (3), Ser396 (3), Thr231 (3), pSer416 (3), pThr217 (3), AA 1-16 (2), Ser202 (2), Thr205 (2), Thr212 (2), pSer198 (2), pSer202 (2), pSer400 (2), pSer409 (2), pSer720 (2), 421/422 (1), AA 240-450 (1), Center (1), N-Term,AA 1-16 (1), Ser198, Ser199, Ser202, Thr205 (1), Ser396, Ser400, Ser404 (1), Ser400 (1), Ser409 (1), Ser720 (1), Thr212, Ser214, Thr217 (1), Thr217 (1), Transcript Variant 4 (1), pSer199, pSer202 (1), pSer519 (1), pThr534 (1), pan (1)