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VEGFR2 antibody (Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase)) (pTyr1175)

Details for Product anti-KDR Antibody No. ABIN967244, Supplier: Log in to see
Antigen
  • vegfr-2
  • KDR
  • 6130401C07
  • Flk-1
  • Flk1
  • Krd-1
  • Ly73
  • VEGFR-2
  • VEGFR2
  • sVEGFR-2
  • Vegfr-2
  • CD309
  • FLK1
  • VEGFR
  • FLK-1
  • flk-1
  • FLK/KDR
  • flk1
  • flk1b
  • kdrb
  • si:busm1-205d10.1
  • si:ch211-254j6.1
  • si:ch211-278f21.4
  • wu:fc31a09
  • fk52c05
  • flk
  • kdr
  • kdra
  • vegfr2
  • vegfr4
  • vegr2
  • wu:fk52c05
  • vascular endothelial growth factor receptor 2
  • kinase insert domain protein receptor
  • kinase insert domain receptor
  • kinase insert domain receptor (a type III receptor tyrosine kinase)
  • kinase insert domain receptor like
  • vascular endothelial growth factor receptor-2
  • vegfr-2
  • Kdr
  • KDR
  • kdr
  • kdrl
Alternatives
anti-Human VEGFR2 antibody for Immunohistochemistry (Frozen Sections)
Epitope
pTyr1175
76
56
52
37
25
23
21
18
18
18
16
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15
13
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5
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4
4
4
4
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3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
596
353
181
22
7
4
4
3
3
2
2
2
1
1
1
1
1
1
1
1
Host
Rabbit
508
138
57
4
2
2
1
Conjugate
This VEGFR2 antibody is un-conjugated
42
32
24
20
16
12
11
9
6
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5
5
5
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4
3
3
3
3
3
3
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3
3
3
2
2
2
2
1
1
Application
Immunohistochemistry (IHC)
439
235
207
191
110
99
40
34
26
24
17
16
11
9
8
7
6
5
3
2
1
1
1
1
1
1
Options
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human VEGFR2 around the phosphorylation site of tyrosine 1175 (K-D-YP-I-V).
Specificity VEGFR2 (phospho-Tyr1175) antibody detects endogenous levels of VEGFR2 only when phosphorylated at tyrosine 1175.
Alternative Name VEGFR2 (KDR Antibody Abstract)
Pathways RTK Signaling, Glycosaminoglycan Metabolic Process
Application Notes IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Background publications Lamalice, Houle, Jourdan, Huot: "Phosphorylation of tyrosine 1214 on VEGFR2 is required for VEGF-induced activation of Cdc42 upstream of SAPK2/p38." in: Oncogene, Vol. 23, Issue 2, pp. 434-45, 2004 (PubMed).

Product cited in: Takahashi, Yamaguchi, Chida, Shibuya: "A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells." in: The EMBO journal, Vol. 20, Issue 11, pp. 2768-78, 2001 (PubMed).