anti-VEGFR2 antibody (Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase)) (pTyr1175)

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Antigen
Synonyms
vegfr-2, KDR, 6130401C07, Flk-1, Flk1, Krd-1, Ly73, VEGFR-2, VEGFR2, sVEGFR-2, Vegfr-2, CD309, FLK1, VEGFR, FLK-1, flk-1, FLK/KDR, flk1, flk1b, kdrb, si:busm1-205d10.1, si:ch211-254j6.1, si:ch211-278f ... show more
vegfr-2, KDR, 6130401C07, Flk-1, Flk1, Krd-1, Ly73, VEGFR-2, VEGFR2, sVEGFR-2, Vegfr-2, CD309, FLK1, VEGFR, FLK-1, flk-1, FLK/KDR, flk1, flk1b, kdrb, si:busm1-205d10.1, si:ch211-254j6.1, si:ch211-278f21.4, wu:fc31a09, fk52c05, flk, kdr, kdra, vegfr2, vegfr4, vegr2, wu:fk52c05 show less
Alternatives
Epitope
pTyr1175
(77), (53), (51), (38), (24), (19), (18), (18), (16), (14), (14), (14), (12), (12), (12), (12), (10), (9), (8), (7), (6), (6), (6), (6), (6), (5), (5), (5), (5), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(550), (294), (164), (6), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Host
Rabbit
(513), (97), (39), (3), (2), (2), (1)
Conjugate
This VEGFR2 antibody is un-conjugated
(39), (22), (19), (16), (12), (11), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC)
(442), (255), (226), (122), (113), (108), (40), (29), (24), (20), (16), (16), (8), (6), (4), (2), (1), (1)
Pubmed 2 references available
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Quantity 100 μg
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Availability Will be delivered in 5 to 7 Business Days
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human VEGFR2 around the phosphorylation site of tyrosine 1175 (K-D-YP-I-V).
Specificity VEGFR2 (phospho-Tyr1175) antibody detects endogenous levels of VEGFR2 only when phosphorylated at tyrosine 1175.
Alternative Name VEGFR2 (KDR Antibody Abstract)
Pathways RTK Signaling
Application Notes IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Takahashi, Yamaguchi, Chida et al.: "A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells." in: The EMBO journal, Vol. 20, Issue 11, pp. 2768-78, 2001 (PubMed).

Background publications Lamalice, Houle, Jourdan et al.: "Phosphorylation of tyrosine 1214 on VEGFR2 is required for VEGF-induced activation of Cdc42 upstream of SAPK2/p38." in: Oncogene, Vol. 23, Issue 2, pp. 434-45, 2004 (PubMed).

Catalog No. ABIN967244
$398.75
Plus shipping costs $45.00

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