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VEGFR2 antibody (Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase)) (pTyr1214)

Details for Product anti-KDR Antibody No. ABIN967245, Supplier: Log in to see
Antigen
  • vegfr-2
  • KDR
  • 6130401C07
  • Flk-1
  • Flk1
  • Krd-1
  • Ly73
  • VEGFR-2
  • VEGFR2
  • sVEGFR-2
  • Vegfr-2
  • CD309
  • FLK1
  • VEGFR
  • FLK-1
  • flk-1
  • FLK/KDR
  • flk1
  • flk1b
  • kdrb
  • si:busm1-205d10.1
  • si:ch211-254j6.1
  • si:ch211-278f21.4
  • wu:fc31a09
  • fk52c05
  • flk
  • kdr
  • kdra
  • vegfr2
  • vegfr4
  • vegr2
  • wu:fk52c05
Alternatives
anti-Human VEGFR2 antibody for Immunohistochemistry (Frozen Sections)
Epitope
pTyr1214
62
49
47
32
24
18
17
16
16
14
13
13
12
12
12
12
9
8
6
6
6
6
5
5
4
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
485
227
134
5
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Host
Rabbit
437
96
23
2
2
1
1
Conjugate
This VEGFR2 antibody is un-conjugated
33
21
16
14
12
11
3
3
3
3
3
3
3
3
1
1
1
1
1
Application
Immunohistochemistry (IHC)
374
227
193
100
95
79
28
23
22
20
17
16
8
6
5
2
1
1
Supplier
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human VEGFR2 around the phosphorylation site of tyrosine 1214 (F-H-YP-D-N).
Specificity VEGFR2 (phospho-Tyr1214) antibody detects endogenous levels of VEGFR2 only when phosphorylated at tyrosine 1214.
Alternative Name VEGFR2 (KDR Antibody Abstract)
Pathways RTK Signaling
Application Notes IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Takahashi, Yamaguchi, Chida et al.: "A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells." in: The EMBO journal, Vol. 20, Issue 11, pp. 2768-78, 2001 (PubMed).

Background publications Lamalice, Houle, Jourdan et al.: "Phosphorylation of tyrosine 1214 on VEGFR2 is required for VEGF-induced activation of Cdc42 upstream of SAPK2/p38." in: Oncogene, Vol. 23, Issue 2, pp. 434-45, 2004 (PubMed).