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V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) (AA 10-193) antibody

Details for Product No. ABIN967267, Supplier: Log in to see
Antigen
  • YES1
  • c-yes
  • hst441
  • p61-yes
  • yes
  • HsT441
  • P61-YES
  • Yes
  • p61-Yes
  • YES
  • c-Yes
  • p60c-yes
Epitope
AA 10-193
29
23
18
13
13
13
10
10
7
6
3
3
2
2
2
2
1
1
1
1
1
Reactivity
Human
136
56
48
2
1
1
Host
Mouse
109
28
2
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
8
7
7
4
4
4
3
3
3
3
3
3
3
3
3
Application
ELISA, Western Blotting (WB)
94
58
33
25
19
9
6
4
4
3
1
1
1
Supplier
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Immunogen Purified recombinant fragment of YES (aa10-193) expressed in E. Coli.
Clone 2F3E6
Isotype IgG1
Purification Ascitic fluid
Alternative Name YES1 (YES1 Antibody Abstract)
Background YES1, v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1. This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22.
Synonyms: Yes, c-yes, HsT441, P61-YES, YES1
Gene ID 7525
Research Area Transcription Factors
Application Notes Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Product cited in: Berger: "Ignorance is bliss? Ethical considerations in therapeutic nondisclosure." in: Cancer investigation, Vol. 23, Issue 1, pp. 94-8, 2005 (PubMed).

Annerén, Cowan, Melton: "The Src family of tyrosine kinases is important for embryonic stem cell self-renewal." in: The Journal of biological chemistry, Vol. 279, Issue 30, pp. 31590-8, 2004 (PubMed).

Background publications Reinehr, Becker, Höngen et al.: "The Src family kinase Yes triggers hyperosmotic activation of the epidermal growth factor receptor and CD95." in: The Journal of biological chemistry, Vol. 279, Issue 23, pp. 23977-87, 2004 (PubMed).