MSI1 antibody (Musashi Homolog 1 (Drosophila)) (AA 221-311)

Details for Product anti-MSI1 Antibody No. ABIN967671, Supplier: Log in to see
Antigen
  • CG5099
  • DMSIDNA
  • Dmel\\CG5099
  • Msi
  • SIDNA
  • anon-EST:Liang-2.35
  • clone 2.35
  • Msi1h
  • Musashi
  • Musashi-1
  • Musashi1
  • XNrp-1
  • nrp-1B
  • Dsim\\GD21224
  • GD21224
  • dsim_GLEANR_4982
  • msi
  • musashi
  • Musahi1
  • m-Msi-1
  • msi1h
  • musashi
  • musashi RNA-binding protein 1
  • GD21224 gene product from transcript GD21224-RA
  • musashi 1
  • musashi homolog 1 (Drosophila)
  • msi
  • msi1
  • Dsim\\msi
  • LOC100352797
  • MSI1
  • Msi1
Alternatives
anti-Rat (Rattus) MSI1 antibody for BioImaging
Epitope
AA 221-311
15
14
13
9
6
5
5
5
4
2
2
1
1
1
Reactivity
Human, Rat (Rattus)
117
17
13
11
5
5
3
1
Host
Mouse
69
47
2
Clonality (Clone)
Monoclonal ()
Conjugate
This MSI1 antibody is un-conjugated
2
2
2
2
2
2
Application
BioImaging (BI), Flow Cytometry (FACS), Western Blotting (WB)
112
48
46
36
34
33
7
3
3
3
1
1
Options
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Brand BD Pharmingen™
Immunogen Human MSI1 a.a. 221-311 Recombinant Protein
Clone N14-47
Isotype IgG1, kappa
Cross-Reactivity (Details) Predicted: Rat
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Triton is a trademark of the Dow Chemical Company.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Please refer to us for technical protocols.
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Alternative Name MSI1 (Musashi-1) (MSI1 Antibody Abstract)
Background The N14-47 monoclonal antibody recognizes RNA-binding protein Musashi homolog 1 (Musashi-1 or MSI1) that represses the translation of particular mRNAs by binding specific RNA sequence motifs. MSI1 contains two RNA-recognition domains at amino acids 20-110 and 109-186. It is expressed in early lineage cells, such as neural stem/progenitor cells, small intestinal stem cells, and mammary stem cells. MSI1 has also been detected in many human cancers, including gliomas, melanomas, colorectal adenomas and adenocarcinomas, suggesting its involvement in cancer development. Western blot analysis and immunofluorescent staining of MSI1 in neural stem cells (NSC) derived from H9 human embryonic stem cells (WiCell, Madison, WI).
Synonyms: Musashi-1, RNA-binding protein Musashi homolog 1, MSI1H
Molecular Weight 39 kDa
Pathways Stem Cell Maintenance
Comment

Related Products: ABIN967389

Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Aqueous buffered solution containing ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store undiluted at 4°C.
Supplier Images
 image for anti-MSI1 antibody (Musashi Homolog 1 (Drosophila)) (AA 221-311) (ABIN967671) NSC lysate was probed with Purified Mouse anti-Human MSI1 monoclonal antibody at conc...
 image for anti-MSI1 antibody (Musashi Homolog 1 (Drosophila)) (AA 221-311) (ABIN967671) NSC were fixed with BD Cytofix™ fixation buffer, permeabilized with 0.1% Triton™-X 10...
Immunofluorescence (IF) image for anti-MSI1 antibody (Musashi Homolog 1 (Drosophila)) (AA 221-311) (ABIN967671) anti-Musashi Homolog 1 (Drosophila) (MSI1) (AA 221-311) antibody (Image 3)
Western Blotting (WB) image for anti-MSI1 antibody (Musashi Homolog 1 (Drosophila)) (AA 221-311) (ABIN967671) anti-Musashi Homolog 1 (Drosophila) (MSI1) (AA 221-311) antibody (Image 4)
Product cited in: Glazer, Wang, Yuan, Yin: "Musashi1: a stem cell marker no longer in search of a function." in: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 17, pp. 2635-9, 2008 (PubMed).

Montgomery, Breault: "Small intestinal stem cell markers." in: Journal of anatomy, Vol. 213, Issue 1, pp. 52-8, 2008 (PubMed).

Okano, Imai, Okabe: "Musashi: a translational regulator of cell fate." in: Journal of cell science, Vol. 115, Issue Pt 7, pp. 1355-9, 2002 (PubMed).