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Details for Product No. ABIN967671

Musashi Homolog 1 (Drosophila) (MSI1) (AA 221-311) antibody

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Antigen
Synonyms
Musashi, Musashi-1, Musashi1, XNrp-1, msi1h, Msi1h, Musahi1, m-Msi-1, CG5099, DMSIDNA, Dmel\\CG5099, Msi, SIDNA, anon-EST:Liang-2.35, clone 2.35, nrp-1B, Dsim\\GD21224, GD21224, dsim_GLEANR_4982, msi, ... show more
Epitope
»Alternatives AA 221-311
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), BioImaging (BI), Flow Cytometry (FACS)
Pubmed 3 references available
Catalog no. ABIN967671
Quantity 0.1 mg
Price
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Immunogen Human MSI1 a.a. 221-311 Recombinant Protein
Clone N14-47
Isotype IgG1, kappa
Cross-Reactivity (Details) Predicted: Rat
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Triton is a trademark of the Dow Chemical Company.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Please refer to us for technical protocols.
Purification Purified from tissue culture supernatant or ascites by affinity chromatography.
Purity Purified
Alternative Name MSI1 (Musashi-1)
Background The N14-47 monoclonal antibody recognizes RNA-binding protein Musashi homolog 1 (Musashi-1 or MSI1) that represses the translation of particular mRNAs by binding specific RNA sequence motifs. MSI1 contains two RNA-recognition domains at amino acids 20-110 and 109-186. It is expressed in early lineage cells, such as neural stem/progenitor cells, small intestinal stem cells, and mammary stem cells. MSI1 has also been detected in many human cancers, including gliomas, melanomas, colorectal adenomas and adenocarcinomas, suggesting its involvement in cancer development. Western blot analysis and immunofluorescent staining of MSI1 in neural stem cells (NSC) derived from H9 human embryonic stem cells (WiCell, Madison, WI).
Synonyms: Musashi-1, RNA-binding protein Musashi homolog 1, MSI1H
Molecular Weight 39 kDa
Comment

Related Products: ABIN967389

Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/ml
Buffer Aqueous buffered solution.
Preservative Sodium azide
Storage 4 °C
Product cited in: Okano, Imai, Okabe: "Musashi: a translational regulator of cell fate." in: Journal of cell science, Vol. 115, Issue Pt 7, pp. 1355-9, 2002 (PubMed).

Montgomery, Breault: "Small intestinal stem cell markers." in: Journal of anatomy, Vol. 213, Issue 1, pp. 52-8, 2008 (PubMed).

Glazer, Wang, Yuan et al.: "Musashi1: a stem cell marker no longer in search of a function." in: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 17, pp. 2635-9, 2008 (PubMed).

Alternatives for antigen "Musashi Homolog 1 (Drosophila) (MSI1)", type "Antibodies"
Hosts (38), (33), (2)
Reactivities (73), (21), (20), (14), (13), (12), (12), (6), (2), (1)
Applications (60), (28), (23), (23), (21), (12), (10), (5), (4), (3), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (5), (4), (3), (3), (2), (2), (2)
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