S100 Calcium Binding Protein P (S100P) (AA 1-95) antibody

Antigen: S100 Calcium Binding Protein P (S100P)

Synonyms: MIG9, S100P, MGC93559

Binding Site: AA 1-95

Clonality: Monoclonal (16)

Host: Mouse

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Catalog no.: ABIN967893

Additional Information

Alternative name: S100P

Immunogen: Human S100P

Format: Liquid

Isotype: IgG1

Clone: 16

Description: The S100 multigene family consists of a number of small dimeric molecules around 100 residues in length. The original members of this family, S100alpha and S100ß, were initially identified in bovine brain. S100P is a novel member of this family which was isolated from human placenta. The S100 family consists of at least 10 members which show a cell-type-specific expression pattern. Most S100 proteins are believed to be involved in cytoplasmic Ca2+ control. S100P consists of 95 amino acids and shares about 50% sequence identity with S100alpha and S100ß. Like other S100 proteins, S100P functions as a homodimer and binds two Ca2+ ions per monomer. Each S100P molecule contains both a low affinity and a high affinity Ca2+ binding site.

Characteristics: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

Molecular Weight: 11 kDa

Comments:

Related Products: ABIN967389

Application Details

Concentration: 250 µg/ml

Purity: Purified

Purification: Purified from tissue culture supernatant or ascites by affinity chromatography.

Buffer: Aqueous buffered solution containing BSA, glycerol.

Preservative: 0.09% Sodium azide.

Storage: Store undiluted at -20° C.

Research Area: Cancer

Restrictions: For Research Use only

Images

Western blot analysis of S100P on a human placenta lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the mouse anti-human S100P antibody.

Immunofluorescence staining of CPAE cells (Bovine pulmonary artery endothelial cells, ATCC CCL-209).

Publications

Product: Becker, Gerke, Kube et al.: "S100P, a novel Ca(2+)-binding protein from human placenta. cDNA cloning, recombinant protein expression and Ca2+ binding properties." in: European journal of biochemistry / FEBS, Vol. 207, Issue 2, pp. 541-7, 1992 (PubMed).

Hellung Schønning, Bévort, Mikkelsen et al.: "Human papillomavirus type 16 E7-regulated genes: regulation of S100P and ADP/ATP carrier protein genes identified by differential-display technology." in: The Journal of general virology, Vol. 81, Issue Pt 4, pp. 1009-15, 2000 (PubMed).