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Tumor Protein, Translationally-Controlled 1 (TPT1) (AA 91-107) antibody

Details for Product No. ABIN967997
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Antigen
Synonyms HRF, TCTP, p02, Trt, p21, p23, PCHK23, TPT1, translationally controlled tumor protein, CG4800, Dmel\\CG4800, dTCTP, TCT1, tctp, fa28a02, id:ibd2078, wu:fa28a02, hrf, MGC79720, Tpt1
Epitope
AA 91-107
(24), (13), (13), (9), (7), (7), (4), (4), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(100), (51), (45), (25), (24), (24), (12), (5), (1), (1), (1)
Host
Mouse
(89), (20)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(8), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application
Western Blotting (WB), Immunofluorescence (IF)
(88), (70), (20), (20), (19), (11), (6), (6), (3), (2), (2), (1)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN967997
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Human HRF
Clone LEP-02
Isotype IgG1
Cross-Reactivity Mouse (Murine)
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Please refer to us for technical protocols.
Purification Purified from tissue culture supernatant or ascites by affinity chromatography.
Purity Purified
Alternative Name HRF
Background One of the most powerful effector mechanisms of the immune system is the reaction initiated by IgE-dependent tissue stimulation of mast cells and basophils. When antigen binds surface IgE on these cells, there is a rapid release of histamine and other mediators that collectively initiate immediate hypersensitivity. This effect is part of a larger response called the late phase reaction (LPR). An IgE-dependent Histamine Releasing Factor (HRF) is present in biological fluids of allergic patients. It causes the release of histamine in IgE-producing cell preparations, where non IgE-producing cells of the same origin do not release histamine. HRF has been reported to be observed as a 21 kDa or 23 kDa protein produced in mouse and human cell lines, respectively. Its sequence does not predict a secretory form, but HRF is found in biological fluids. Neither the exact function of this protein nor the method of its secretion is known.
Synonyms: Histamine Releasing Factor
Molecular Weight 23 kDa
Comment

Related Products: ABIN968533, ABIN967389

Restrictions For Research Use only
Format Liquid
Concentration 250 µg/ml
Buffer Aqueous buffered solution containing BSA, glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Supplier Images
anti-Tumor Protein, Translationally-Controlled 1 (TPT1) (AA 91-107) antibody Western blot analysis of HRF on a A431 cell lysate (Human epithelial carcinoma, ATCC CRL-1555). Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the mouse anti-HRF antibody.
anti-Tumor Protein, Translationally-Controlled 1 (TPT1) (AA 91-107) antibody (2) Immunofluorescence staining of A431 cells (Human epithelial carcinoma, ATCC CRL-1555).
anti-Tumor Protein, Translationally-Controlled 1 (TPT1) (AA 91-107) antibody (3) anti-Tumor Protein, Translationally-Controlled 1 (TPT1) (AA 91-107) antibody (Image 3)
Product cited in: MacDonald, Rafnar, Langdon et al.: "Molecular identification of an IgE-dependent histamine-releasing factor." in: Science (New York, N.Y.), Vol. 269, Issue 5224, pp. 688-90, 1995 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN967997
Contact our Customer Service for availability and price in your country.
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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