Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Add to Basket
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN968022

Ankyrin Repeat and Sterile alpha Motif Domain Containing 1B (ANKS1B) (AA 107-268) antibody

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms AIDA, AIDA-1, ANKS2, EB-1, EB1, cajalin-2, AIDA-1b, C030032C09Rik, E530015N03Rik, ENSMUSG00000078431, Gm10937, Gm1555, RGD1565556
Epitope
»Alternatives AA 107-268
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (ffpe))
Pubmed 5 references available
Catalog no. ABIN968022
Quantity 150 µg
Price
Contact our Customer Service for availability and price in your country.
Shipping to
Immunogen Human EB1
Clone 5
Isotype IgG1
Cross-Reactivity Chicken, Mouse (Murine), Rat (Rattus)
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Purification Purified from tissue culture supernatant or ascites by affinity chromatography.
Purity Purified
Alternative Name EB1
Background Familial adenomatous polyposis is an autosomal inherited disease characterized by mutations in the APC (adenomatous polyposis coli) gene. Individuals with this disease are predisposed to colorectal polyps and cancer. It has been proposed that disruption of the APC gene plays a role in the disease. APC is a large coiled-coil protein that interacts, via its carboxy terminus, with catenins and with the protein, EB1. This 30 kDa protein was discovered as a result of its strong binding to the C-terminal domain of APC. Like the APC-binding proteins beta-Catenin and pp120Cas, EB1 may play an essential role in modulating APC activity and tumorigenesis. This antibody is routinely tested by western blot analysis.
Molecular Weight 30 kDa
Comment

Related Products: ABIN968536, ABIN967389

Restrictions For Research Use only
Format Liquid
Concentration 250 µg/ml
Buffer Aqueous buffered solution containing BSA, glycerol.
Preservative Sodium azide
Storage -20 °C
Product cited in: Su, Huang, Fair et al.: "Alternatively spliced variants of prostate-specific membrane antigen RNA: ratio of expression as a potential measurement of progression." in: Cancer research, Vol. 55, Issue 7, pp. 1441-3, 1995 (PubMed).

Mamane, Grandvaux, Hernandez et al.: "Repression of IRF-4 target genes in human T cell leukemia virus-1 infection." in: Oncogene, Vol. 21, Issue 44, pp. 6751-65, 2002 (PubMed).

Askham, Vaughan, Goodson et al.: "Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome." in: Molecular biology of the cell, Vol. 13, Issue 10, pp. 3627-45, 2002 (PubMed).

Komarova, Akhmanova, Kojima et al.: "Cytoplasmic linker proteins promote microtubule rescue in vivo." in: The Journal of cell biology, Vol. 159, Issue 4, pp. 589-99, 2002 (PubMed).

Etienne-Manneville, Hall: "Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity." in: Nature, Vol. 421, Issue 6924, pp. 753-6, 2003 (PubMed).

Alternatives for antigen "Ankyrin Repeat and Sterile alpha Motif Domain Containing 1B (ANKS1B)", type "Antibodies"
Hosts (22), (2)
Reactivities (23), (14), (12), (12), (1)
Applications (15), (10), (4), (4), (4), (2), (2)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (2), (2), (1), (1), (1)
Beacon