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GFAP antibody (Glial Fibrillary Acidic Protein) (AA 418-432)

Details for Product anti-GFAP Antibody No. ABIN968040, Supplier: Log in to see
Antigen
  • GFAP
  • AI836096
  • cb345
  • etID36982.3
  • gfapl
  • wu:fb34h11
  • wu:fk42c12
  • xx:af506734
  • zgc:110485
Epitope
AA 418-432
70
69
29
28
23
13
13
6
6
6
5
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Chicken, Human, Mouse (Murine), Rat (Rattus)
561
214
204
91
89
38
26
24
19
16
11
10
6
5
4
4
3
3
2
2
1
1
1
1
1
1
1
1
Host
Mouse
335
295
27
24
4
3
2
Clonality (Clone)
Monoclonal ()
Conjugate
This GFAP antibody is un-conjugated
29
23
19
11
11
11
7
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
2
2
1
1
1
1
Application
Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
483
281
167
166
164
151
70
48
33
21
14
12
11
10
8
7
7
6
5
3
1
1
1
1
1
1
1
1
Supplier
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Immunogen Human GFAP aa. 418-432
Clone 52-GFAP
Isotype IgG1
Cross-Reactivity Chicken, Mouse (Murine), Rat (Rattus)
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Alternative Name GFAP (GFAP Antibody Abstract)
Background The cytoskeleton is an array of highly ordered filaments that maintains the shape, structure, and functionality of cells. There are three major types of filaments: actin filaments, microtubules, and intermediate filaments. The distinctions among them are based on protein composition and arrangements. Glial fibrillary acidic protein (GFAP) is a 50 kDa component of the intermediate filaments and was originally identified in astrocytes. The overall structure of GFAP, which confirms its similarities to other intermediate filament proteins, indicates a central rod of about 130 amino acids flanked by coiled regions. GFAP has been extensively used as an immunohistochemical marker for tumors derived from astroglia. This antibody is routinely tested by western blot analysis.
Molecular Weight 50 kDa
Research Area Stem Cells, Cytoskeleton, Glia marker, Cell/Tissue Markers, Neurology
Pathways
Comment

Related Products: ABIN967389, ABIN968552

Restrictions For Research Use only
Format Liquid
Concentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store undiluted at -20° C.
Supplier Images
Western Blotting (WB) image for anti-GFAP antibody (Glial Fibrillary Acidic Protein) (AA 418-432) (ABIN968040) Western blot analysis of GFAP on SW13 lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1...
 image for anti-GFAP antibody (Glial Fibrillary Acidic Protein) (AA 418-432) (ABIN968040) Immunofluroescent staining of Rabbit Brain tissue.
Background publications Reeves, Helman, Allison et al.: "Molecular cloning and primary structure of human glial fibrillary acidic protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 13, pp. 5178-82, 1989 (PubMed).