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Caveolin 2 antibody (AA 42-162)

CAV2 Reactivity: Human, Mouse, Rat WB, IHC, IF, IP Host: Mouse Monoclonal 65-Caveolin 2 unconjugated
Catalog No. ABIN968108
  • Target See all Caveolin 2 (CAV2) Antibodies
    Caveolin 2 (CAV2)
    Binding Specificity
    • 15
    • 10
    • 9
    • 9
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 42-162
    Reactivity
    • 70
    • 29
    • 27
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 74
    • 8
    • 3
    • 1
    Mouse
    Clonality
    • 68
    • 18
    Monoclonal
    Conjugate
    • 33
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Caveolin 2 antibody is un-conjugated
    Application
    • 47
    • 17
    • 14
    • 13
    • 12
    • 12
    • 9
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    Cross-Reactivity
    Mouse (Murine), Rat (Rattus)
    Characteristics
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Human Caveolin 2 aa. 42-162
    Clone
    65-Caveolin 2
    Isotype
    IgG1
    Top Product
    Discover our top product CAV2 Primary Antibody
  • Comment

    Related Products: ABIN967389

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store undiluted at -20° C.
  • Tauchi-Sato, Ozeki, Houjou, Taguchi, Fujimoto: "The surface of lipid droplets is a phospholipid monolayer with a unique Fatty Acid composition." in: The Journal of biological chemistry, Vol. 277, Issue 46, pp. 44507-12, (2002) (PubMed).

    Woodman, Park, Cohen, Cheung, Chandra, Shirani, Tang, Jelicks, Kitsis, Christ, Factor, Tanowitz, Lisanti: "Caveolin-3 knock-out mice develop a progressive cardiomyopathy and show hyperactivation of the p42/44 MAPK cascade." in: The Journal of biological chemistry, Vol. 277, Issue 41, pp. 38988-97, (2002) (PubMed).

    Zschocke, Manthey, Bayatti, van der Burg, Goodenough, Behl: "Estrogen receptor alpha-mediated silencing of caveolin gene expression in neuronal cells." in: The Journal of biological chemistry, Vol. 277, Issue 41, pp. 38772-80, (2002) (PubMed).

    Kiss, Túri, Müllner, Tímár: "Caveolin isoforms in resident and elicited rat peritoneal macrophages." in: European journal of cell biology, Vol. 79, Issue 5, pp. 343-9, (2000) (PubMed).

    Das, Lewis, Scherer, Lisanti: "The membrane-spanning domains of caveolins-1 and -2 mediate the formation of caveolin hetero-oligomers. Implications for the assembly of caveolae membranes in vivo." in: The Journal of biological chemistry, Vol. 274, Issue 26, pp. 18721-8, (1999) (PubMed).

    Scherer, Okamoto, Chun, Nishimoto, Lodish, Lisanti: "Identification, sequence, and expression of caveolin-2 defines a caveolin gene family." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 1, pp. 131-5, (1996) (PubMed).

  • Target
    Caveolin 2 (CAV2)
    Alternative Name
    Caveolin 2 (CAV2 Products)
    Synonyms
    CAV antibody, AI447843 antibody, cav-2 antibody, zgc:86696 antibody, wu:fc52e01 antibody, caveolin-2 antibody, CAV-2 antibody, Caveolin-2 antibody, Cav-2 antibody, cav antibody, cav2 antibody, caveolin 2 antibody, caveolin 2 L homeolog antibody, caveolin-2 antibody, Caveolin-2 antibody, CAV2 antibody, Cav2 antibody, cav2.L antibody, cav2 antibody, LOC100093133 antibody, cav-2 antibody
    Background
    Identified as a tyrosine phosphorylated protein in Rous sarcoma virus- transformed chick embryo fibroblasts (CEF), caveolin is now known to be ubiquitously expressed. Caveolin (also known as VIP21) localizes to non-clathrin membrane invaginations (caveolae) on the inner surface of the plasma membrane. This transmembrane protein plays a structural role in these specializations. Caveolin is also present at the trans-Golgi network (TGN) and similar quantities are found in apically and basolaterally destined transport vesicles. Caveolin is part of a complex containing glycosylphosphatidylinositol (GPI)-linked molecules and cytoplasmic signaling proteins. Caveolin is a transmembrane adaptor molecule that can simultaneously recognize GPI-linked proteins and interact with downstream cytoplasmic signaling molecules, such as c-yes, Annexin II, and hetero-trimeric G proteins. Although caveolin 2 is similar to caveolin 1 in distribution and tissue expression, caveolin 2 is most abundant in adipose tissue and its expression is up-regulated upon differentiation. This antibody has been reported to recognize an epitope located within region 79-88 of caveolin 2.
    Molecular Weight
    20 kDa
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development
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