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ENAH antibody (AA 415-541)

ENAH Reactivity: Human, Mouse, Rat, Chicken WB, IHC, IP, IF Host: Mouse Monoclonal 21-Mena unconjugated
Catalog No. ABIN968115
  • Target See all ENAH Antibodies
    ENAH (Enabled Homolog (ENAH))
    Binding Specificity
    • 13
    • 10
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 415-541
    Reactivity
    • 45
    • 21
    • 19
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Chicken
    Host
    • 41
    • 4
    Mouse
    Clonality
    • 41
    • 4
    Monoclonal
    Conjugate
    • 21
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ENAH antibody is un-conjugated
    Application
    • 44
    • 20
    • 13
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
    Cross-Reactivity
    Human, Rat (Rattus), Chicken
    Characteristics
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Mouse Mena aa. 415-541
    Clone
    21-Mena
    Isotype
    IgA
    Top Product
    Discover our top product ENAH Primary Antibody
  • Comment

    Related Products: ABIN968552, ABIN967389

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store undiluted at -20° C.
  • Howe, Hogan, Juliano: "Regulation of vasodilator-stimulated phosphoprotein phosphorylation and interaction with Abl by protein kinase A and cell adhesion." in: The Journal of biological chemistry, Vol. 277, Issue 41, pp. 38121-6, (2002) (PubMed).

    García Arguinzonis, Galler, Walter, Reinhard, Simm: "Increased spreading, Rac/p21-activated kinase (PAK) activity, and compromised cell motility in cells deficient in vasodilator-stimulated phosphoprotein (VASP)." in: The Journal of biological chemistry, Vol. 277, Issue 47, pp. 45604-10, (2002) (PubMed).

    Drees, Friederich, Fradelizi, Louvard, Beckerle, Golsteyn: "Characterization of the interaction between zyxin and members of the Ena/vasodilator-stimulated phosphoprotein family of proteins." in: The Journal of biological chemistry, Vol. 275, Issue 29, pp. 22503-11, (2000) (PubMed).

    Gertler, Niebuhr, Reinhard, Wehland, Soriano: "Mena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamics." in: Cell, Vol. 87, Issue 2, pp. 227-39, (1996) (PubMed).

  • Target
    ENAH (Enabled Homolog (ENAH))
    Alternative Name
    Mena (ENAH Products)
    Synonyms
    ENA antibody, MENA antibody, NDPP1 antibody, AI464316 antibody, AW045240 antibody, Mena antibody, Ndpp1 antibody, WBP8 antibody, id:ibd2798 antibody, si:ch211-215p14.1 antibody, zgc:103638 antibody, ENAH, actin regulator antibody, enabled homolog (Drosophila) antibody, Enah antibody, ENAH antibody, enah antibody
    Background
    Abl and Disabled (Dab) are essential for correct axonal connections during Drosophila development. Mutations in Enabled (Ena) rescue the genetic defects caused by mutated Abl and Dab. Mena (Mammalian Ena) is a protein with significant homology to Eva, VASP, and WASP proteins. The murine Mena gene predicts a protein of 541 amino acids. However, two additional exons that could introduce 246 amino acids onto the C-terminal region have been identified. Homology searches identified two EVH domains (Ena-Vasp homology), one near each terminus of Mena. Antibodies to Mena detect 80 kDa, 88 kDa, and 140 kDa protein with the 80 kDa and 88 kDa proteins being widely expressed and the 140 kDa protein reportedly mainly found in brain tissue. Like VASP, Mena is localized to focal contacts and, when ectopically expressed, induces the formation of F-actin outgrowths in fibroblasts. This antibody is routinely tested by Western blot analysis.
    Synonyms: Mammalian Ena (Enabled)
    Molecular Weight
    140, 88, 80 kDa
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