You are viewing an incomplete version of our website. Please click to reload the website as full version.

N-Acetyltransferase 1 (Arylamine N-Acetyltransferase) (NAT1) (AA 672-830) antibody

Details for Product No. ABIN968149, Supplier: Login to see New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Synonyms DRCF-6, Eif4g2, NAT1, Nat-1, Nat, AAC1, MNAT, NAT-1, NATI, AT-I
AA 672-830
(25), (15), (11), (8), (5), (3), (2), (2), (1), (1), (1), (1)
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(73), (12), (12), (1), (1), (1)
(47), (23), (3)
Clonality (Clone)
Monoclonal ()
(4), (4), (4), (4), (4), (4)
Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(54), (45), (18), (4), (3), (2), (1), (1), (1), (1), (1)
Pubmed 3 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 150 μg
Shipping to United States ( )
Immunogen Human NAT1 aa. 672-830
Clone 35-T1
Isotype IgG1
Cross-Reactivity Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine)
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Alternative Name NAT1 (NAT1 Antibody Abstract)
Background EIF-4 proteins are required for recognition of mRNA and acceleration of protein translation. This group of proteins consists of the RNA helicase eIF-4A, the RNA-binding protein eIF-4B, the cap-binding protein eIF-4E, and eIF-4G (p220). NAT1 (Novel APOBEC-1 Target no. 1), also known as DAP-5 (Death Associated Protein -5), is homologous to eIF-4G. Amino acid sequence comparison of NAT1 and eIF-4 shows that NAT1 lacks an eIF-4G N-terminal region. This region mediates eIF-4G association with eIF-4E. The highest degree of homology is within the central portions of NAT1 and eIF-4G, while the lowest degree of homology occurs at the C-terminus. NAT1 more closely resembles a cleaved form of eIF-4G that is involved in cap-independent translation. It is thought that NAT1 is involved in the repression of translation via its inhibition of both cap-dependent and cap-independent translation.
Synonyms: Novel APOBEC-1 Target no. 1, DAP-5, Death Associated Protein -5
Molecular Weight 100 kDa
Research Area Signaling, Metabolism, Amino Acids

Related Products: ABIN968535, ABIN967389

Restrictions For Research Use only
Format Liquid
Concentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store undiluted at -20° C.
Supplier Images
Western Blotting (WB) image for anti-N-Acetyltransferase 1 (Arylamine N-Acetyltransferase) (NAT1) (AA 672-830) antibody (ABIN968149) Western blot analysis of NAT1 on a HeLa cell lysate (Human cervical epitheloid carcin...
Immunofluorescence (IF) image for anti-N-Acetyltransferase 1 (Arylamine N-Acetyltransferase) (NAT1) (AA 672-830) antibody (ABIN968149) Immunofluorescence staining of mouse macrophages.
 image for anti-N-Acetyltransferase 1 (Arylamine N-Acetyltransferase) (NAT1) (AA 672-830) antibody (ABIN968149) anti-N-Acetyltransferase 1 (Arylamine N-Acetyltransferase) (NAT1) (AA 672-830) antibody (Image 3)
Product cited in: Henis-Korenblit, Strumpf, Goldstaub et al.: "A novel form of DAP5 protein accumulates in apoptotic cells as a result of caspase cleavage and internal ribosome entry site-mediated translation." in: Molecular and cellular biology, Vol. 20, Issue 2, pp. 496-506, 2000 (PubMed).

Levy-Strumpf, Deiss, Berissi et al.: "DAP-5, a novel homolog of eukaryotic translation initiation factor 4G isolated as a putative modulator of gamma interferon-induced programmed cell death." in: Molecular and cellular biology, Vol. 17, Issue 3, pp. 1615-25, 1997 (PubMed).

Yamanaka, Poksay, Arnold et al.: "A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzyme." in: Genes & development, Vol. 11, Issue 3, pp. 321-33, 1997 (PubMed).

Catalog No. ABIN968149
Contact our Customer Service for availability and price in your country.

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)