Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1) (AA 1-112) antibody
Alternatives Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
|2 references available|
|Quantity||150 µg (250 µg/ml) (Variants)|
|Price||Product not available in this region.|
|Alternative name||SIII p15|
|Immunogen||Human SIII p15|
|Cross-Reactivity||Dog (Canine), Rat (Rattus), Mouse (Murine), Frog|
|Description||SIII p15 is one of three polypeptides that comprise the approximate 140kDa RNA polymerase II transcription factor SIII. The other two polypeptides have the molecular weights of 110kDa and 18kDa. All three polypeptides are required for transcription factor SIII function. Although the polypeptides were identified and purified from rat liver nuclear extracts, tissue expression of this transcription factor appears to be widespread. RNA polymerase II recognizes the SIII transcription factor and in turn initiates transcription from these correctly initiated transcripts. A yeast transcription factor designated YES may be the yeast homolog to SIII.|
1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
|Molecular Weight||15 kDa|
Related Products: ABIN968587, ABIN967389
|Purification||Purified from tissue culture supernatant or ascites by affinity chromatography.|
|Buffer||Aqueous buffered solution containing BSA, glycerol.|
|Preservative||0.09% Sodium azide.|
|Storage||Store undiluted at -20° C.|
|Restrictions||For Research Use only|
Bradsher, Jackson, Conaway et al.: "RNA polymerase II transcription factor SIII. I. Identification, purification, and properties." in: The Journal of biological chemistry, Vol. 268, Issue 34, pp. 25587-93, 1994 (PubMed).
Kuznetsova, Meller, Schnell et al.: "von Hippel-Lindau protein binds hyperphosphorylated large subunit of RNA polymerase II through a proline hydroxylation motif and targets it for ubiquitination." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 5, pp. 2706-11, 2003 (PubMed).
|Hosts||Rabbit (12), Chicken (2)|
|Reactivities||Human (12), Mouse (Murine) (6), Rat (Rattus) (5), Chicken (2), Cow (Bovine) (2), Dog (Canine) (2), Xenopus laevis (2), Zebrafish (2), Fruit Fly (Drosophila melanogaster) (1)|
|Applications||Western Blotting (WB) (12), ELISA (6), Immunohistochemistry (IHC) (5)|
|Epitopes||C-Term (2), Internal Region (1), N-Term (1)|