Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1) (AA 1-112) antibody

Details for Product No. ABIN968162
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Antigen
Synonyms 2610043E24Rik, 2610301I15Rik, AA407206, AI987979, AW049146, SIII, eloC, TCEB1, fb09f09, wu:fb09f09, zgc:111990, zgc:92635
Epitope
AA 1-112
(8), (7), (2), (1), (1), (1)
Reactivity
Human
(25), (5), (4), (2), (2), (2), (2), (2), (1)
Host
Mouse
(21), (4), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1)
Application
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
(21), (11), (10), (1), (1)
Pubmed 2 references available
Quantity 150 μg
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Catalog No. ABIN968162
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Immunogen Human SIII p15
Clone 56
Isotype IgG1
Cross-Reactivity Dog (Canine), Rat (Rattus), Mouse (Murine), Frog
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Purification Purified from tissue culture supernatant or ascites by affinity chromatography.
Alternative Name SIII p15
Background SIII p15 is one of three polypeptides that comprise the approximate 140kDa RNA polymerase II transcription factor SIII. The other two polypeptides have the molecular weights of 110kDa and 18kDa. All three polypeptides are required for transcription factor SIII function. Although the polypeptides were identified and purified from rat liver nuclear extracts, tissue expression of this transcription factor appears to be widespread. RNA polymerase II recognizes the SIII transcription factor and in turn initiates transcription from these correctly initiated transcripts. A yeast transcription factor designated YES may be the yeast homolog to SIII.
Molecular Weight 15 kDa
Comment

Related Products: ABIN968587, ABIN967389

Restrictions For Research Use only
Format Liquid
Concentration 250 µg/ml
Buffer Aqueous buffered solution containing BSA, glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Supplier Images
anti-Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1) (AA 1-112) antibody Immunofluorescent staining of Human Fibroblasts.
anti-Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1) (AA 1-112) antibody (2) Western blot analysis of Elongin C/SIII p15 on HepG2 cell lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of Elongin C/SIII p15 antibody
anti-Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1) (AA 1-112) antibody (3) anti-Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1) (AA 1-112) antibody (Image 3)
Product cited in: Bradsher, Jackson, Conaway et al.: "RNA polymerase II transcription factor SIII. I. Identification, purification, and properties." in: The Journal of biological chemistry, Vol. 268, Issue 34, pp. 25587-93, 1994 (PubMed).

Kuznetsova, Meller, Schnell et al.: "von Hippel-Lindau protein binds hyperphosphorylated large subunit of RNA polymerase II through a proline hydroxylation motif and targets it for ubiquitination." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 5, pp. 2706-11, 2003 (PubMed).

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