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Neurogenin 3 antibody (NEUROG3) (AA 9-148)

Details for Product anti-NEUROG3 Antibody No. ABIN968179, Supplier: Login to see New
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Synonyms NEUROG3, ngn3, atoh5, ngn-3, bhlha7, math4b, neurog3, Ngn3, Atoh5, Math4B, NGN-3, bHLHa7, Relax, atoh4, ngn2, ngn3a
AA 9-148
(26), (14), (14), (14), (13), (13), (12), (5), (5), (3), (2), (2), (2), (1), (1), (1)
Human, Mouse (Murine), Rat (Rattus)
(100), (34), (16), (2), (1), (1), (1), (1)
(80), (29), (2)
Clonality (Clone)
Monoclonal ()
This Neurogenin 3 antibody is un-conjugated
(6), (6), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(75), (56), (43), (14), (11), (8), (7), (3), (2), (1), (1), (1)
Pubmed 4 references available
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Quantity 50 μg
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Immunogen Mouse Neurogenin 3 aa. 9-148
Clone 7-Neurogenin 3
Isotype IgG1
Cross-Reactivity Rat (Rattus), Human
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Alternative Name Neurogenin 3 (NEUROG3 Antibody Abstract)
Background Neurogenins are a family of atonal-related bHLH (basic helix-loop-helix) proteins that have been implicated in vertebrate neurogenesis. Members of this family include Neurogenin 1, 2, and 3. In a search for proteins that control early neuronal development, Neurogenin 1 was identified as a novel, Neuro-D-related bHLH protein that is expressed prior to Neuro-D in mouse and Xenopus. Identification of Neurogenins 2 and 3 defined the Neurogenin family. Analysis indicates that neurogenin gene expression defines progenitor populations in the developing nervous system and that neurogenin proteins and Neuro-D function in a cascade. Neurogenin proteins are expressed prior to Neuro-D and subsequent to another bHLH protein, MASH7. Neurogenin 3 is a 244 amino acid, 23 kDa protein that is expressed in fetal, neonatal, and neural tissues, as well as in several neuronal cell lines. Temporal and spatial expression of the neurogenin proteins is critical to proper neural determination and differentiation. This antibody is routinely tested by western blot analysis.
Molecular Weight 23 kDa

Related Products: ABIN968539, ABIN967389

Restrictions For Research Use only
Format Liquid
Concentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store undiluted at -20° C.
Supplier Images
Western Blotting (WB) image for anti-Neurogenin 3 antibody (NEUROG3) (AA 9-148) (ABIN968179) Western blot analysis of Neurogenin 3 on PC12 cell lysate. Lane 1: 1:500, lane 2: 1:1...
 image for anti-Neurogenin 3 antibody (NEUROG3) (AA 9-148) (ABIN968179) anti-Neurogenin 3 (NEUROG3) (AA 9-148) antibody (Image 2)
Western Blotting (WB) image for anti-Neurogenin 3 antibody (NEUROG3) (AA 9-148) (ABIN968179) anti-Neurogenin 3 (NEUROG3) (AA 9-148) antibody (Image 3)
Product cited in: Ma, Sommer, Cserjesi et al.: "Mash1 and neurogenin1 expression patterns define complementary domains of neuroepithelium in the developing CNS and are correlated with regions expressing notch ligands." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 17, Issue 10, pp. 3644-52, 1997 (PubMed).

Cau, Gradwohl, Fode et al.: "Mash1 activates a cascade of bHLH regulators in olfactory neuron progenitors." in: Development (Cambridge, England), Vol. 124, Issue 8, pp. 1611-21, 1997 (PubMed).

Sommer, Ma, Anderson: "neurogenins, a novel family of atonal-related bHLH transcription factors, are putative mammalian neuronal determination genes that reveal progenitor cell heterogeneity in the developing CNS and PNS." in: Molecular and cellular neurosciences, Vol. 8, Issue 4, pp. 221-41, 1997 (PubMed).

Ma, Kintner, Anderson: "Identification of neurogenin, a vertebrate neuronal determination gene." in: Cell, Vol. 87, Issue 1, pp. 43-52, 1996 (PubMed).

Catalog No. ABIN968179
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