NCOA3 antibody

Catalog No. ABIN968949

Product Details anti-NCOA3 Antibody

Target: NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NCOA3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: purified

Immunogen: Purified recombinant fragment of human AIB1 expressed in E. coli.

Clone: 5H3

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

References for anti-NCOA3 antibody (ABIN968949)

Pu, Ye, Spitz, Wang, Gu, Lippman, Hildebrandt, Hong, Minna, Roth, Yang, Wu: "Predictors of survival in never-smokers with non-small cell lung cancer: a large-scale, two-phase genetic study." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 21, pp. 5983-91, (2012) (PubMed).

Bai, Wong: "Detection and quantification of heteroplasmic mutant mitochondrial DNA by real-time amplification refractory mutation system quantitative PCR analysis: a single-step approach." in: Clinical chemistry, Vol. 50, Issue 6, pp. 996-1001, (2004) (PubMed).

Target Details for NCOA3

Target: NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))

Alternative Name: AIB1 (NCOA3 Products)

Synonyms: NCOA3 antibody, ACTR antibody, AIB-1 antibody, AIB1 antibody, CAGH16 antibody, CTG26 antibody, KAT13B antibody, RAC3 antibody, SRC-3 antibody, SRC3 antibody, TNRC14 antibody, TNRC16 antibody, TRAM-1 antibody, bHLHe42 antibody, pCIP antibody, 2010305B15Rik antibody, AW321064 antibody, Actr antibody, Aib1 antibody, Rac3 antibody, Src3 antibody, Tram-1 antibody, Tram1 antibody, p/Cip antibody, pCip antibody, actr antibody, aib-1 antibody, aib1 antibody, cagh16 antibody, ctg26 antibody, kat13b antibody, pcip antibody, rac3 antibody, src-3 antibody, src3 antibody, tnrc14 antibody, tnrc16 antibody, tram-1 antibody, xSRC-3 antibody, nuclear receptor coactivator 3 antibody, nuclear receptor coactivator 3 S homeolog antibody, NCOA3 antibody, Ncoa3 antibody, ncoa3.S antibody

Background:

Description: The poly Q polymorphism in AIB1 (amplified in breast cancer) gene is usually assessed by fragment length analysis which does not reveal the actual sequence variation. The purpose of this study is to investigate the sequence variation of poly Q encoding region in breast cancer cell lines at single molecule level, and to determine if the sequence variation is related to AIB1 gene amplification.

Aliases: AIB, AIB1, ANIB1

Molecular Weight: 155 kDa

Gene ID: 116833

HGNC: 116833

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha