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ATF2 antibody

ATF2 Reactivity: Human, Mouse WB, IHC, ELISA Host: Mouse Monoclonal 4F12 unconjugated
Catalog No. ABIN968968
  • Target See all ATF2 Antibodies
    ATF2 (Activating Transcription Factor 2 (ATF2))
    Reactivity
    • 294
    • 228
    • 206
    • 16
    • 12
    • 11
    • 8
    • 7
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 327
    • 11
    • 2
    • 1
    Mouse
    Clonality
    • 313
    • 28
    Monoclonal
    Conjugate
    • 153
    • 20
    • 16
    • 16
    • 16
    • 15
    • 15
    • 15
    • 13
    • 12
    • 9
    • 8
    • 8
    • 8
    • 8
    • 5
    • 4
    This ATF2 antibody is un-conjugated
    Application
    • 240
    • 117
    • 112
    • 111
    • 75
    • 61
    • 59
    • 35
    • 33
    • 22
    • 15
    • 10
    • 6
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human ATF2 expressed in E. coli.
    Clone
    4F12
    Isotype
    IgG1
    Top Product
    Discover our top product ATF2 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Chen, Takeuchi, Moroi, Hayashida, Kido, Chen, Tomoeda, Uenotsuchi, Tu, Furue, Urabe: "Overexpression of phosphorylated-ATF2 and STAT3 in cutaneous squamous cell carcinoma, Bowen's disease and basal cell carcinoma." in: Journal of dermatological science, Vol. 51, Issue 3, pp. 210-5, (2008) (PubMed).

    Bhoumik, Singha, OConnell, Ronai: "Regulation of TIP60 by ATF2 modulates ATM activation." in: The Journal of biological chemistry, Vol. 283, Issue 25, pp. 17605-14, (2008) (PubMed).

  • Target
    ATF2 (Activating Transcription Factor 2 (ATF2))
    Alternative Name
    ATF2 (ATF2 Products)
    Synonyms
    CRE-BP1 antibody, CREB2 antibody, HB16 antibody, TREB7 antibody, CG12850 antibody, CG3749 antibody, dATF-2 antibody, DmelCG30420 antibody, CG30420 antibody, CHN1 antibody, Atf-2 antibody, CRE-BP antibody, Creb2 antibody, D130078H02Rik antibody, D18875 antibody, Tg(Gzma-Klra1)7Wum antibody, mXBP antibody, atf2-A antibody, atf2l antibody, activating transcription factor 2 antibody, Activating transcription factor-2 antibody, activating transcription factor 2 S homeolog antibody, ATF2 antibody, Atf-2 antibody, Atf2 antibody, atf2.S antibody, atf2 antibody
    Background

    Description: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined.Tissue specificity: Abundant expression seen in the brain.

    Aliases: HB16, CREB2, TREB7, CRE-BP1, MGC111558, ATF2

    Molecular Weight
    55 kDa
    Gene ID
    1386
    HGNC
    1386
    Pathways
    MAPK Signaling, RTK Signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
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