You are viewing an incomplete version of our website. Please click to reload the website as full version.

BMP4 antibody (Bone Morphogenetic Protein 4)

Details for Product anti-BMP4 Antibody No. ABIN968986, Supplier: Log in to see
Antigen
  • bmp-2
  • bmp-4
  • Bmp-4
  • BMP-4
  • bmp2
  • bmp2-4
  • bmp2b
  • BMP2B
  • Bmp2b
  • Bmp2b-1
  • BMP2B1
  • bmp2b1
  • Bmp2b1
  • BMP4
  • bmp4
  • BOMPR4A
  • cb670
  • MCOPS6
  • ofc11
  • OFC11
  • XBMP-4
  • xbmp4
  • zbmp-2
  • zbmp-4
  • zbmp2
  • zgc:100779
  • zyme
  • ZYME
Reactivity
Human
200
85
47
15
12
9
8
7
3
3
1
1
1
1
1
1
1
1
1
Host
Mouse
164
96
9
1
Clonality (Clone)
Monoclonal ()
Conjugate
This BMP4 antibody is un-conjugated
22
19
9
6
4
4
3
3
3
3
3
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
193
153
58
42
30
19
11
11
9
4
3
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Immunogen Purified recombinant fragment of human BMP4 expressed in E. coli.
Clone 10F4B4
Isotype IgG1
Purification Ascites
Alternative Name BMP4 (BMP4 Antibody Abstract)
Background The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors.BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.
Molecular Weight 64 kDa
Gene ID 652
HGNC 652
Research Area Organogenesis, Growth Factors, Angiogenesis, Signaling
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
Western Blotting (WB) image for anti-BMP4 antibody (Bone Morphogenetic Protein 4) (ABIN968986) Figure 1: Western blot analysis using BMP4 mouse mAb against BMP4-hIgGFc transfected ...
Product cited in: Solmesky, Abekasis, Bulvik, Weil: "Bone morphogenetic protein signaling is involved in human mesenchymal stem cell survival in serum-free medium." in: Stem cells and development, Vol. 18, Issue 9, pp. 1283-92, 2009 (PubMed).

Yerges, Klei, Cauley, Roeder, Kammerer, Moffett, Ensrud, Nestlerode, Marshall, Hoffman, Lewis, Lang, Barrett-Connor, Ferrell, Orwoll, Zmuda: "High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 24, Issue 12, pp. 2039-49, 2009 (PubMed).

Background publications Oida, Iimura, Maruoka, Takeda, Sasaki: "Cloning and sequence of bone morphogenetic protein 4 (BMP-4) from a human placental cDNA library." in: DNA sequence : the journal of DNA sequencing and mapping, Vol. 5, Issue 5, pp. 273-5, 1995 (PubMed).