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CD33 Molecule (CD33) antibody

Details for Product No. ABIN969020, Supplier: Log in to see
Antigen
  • Siglec-3
  • gp67
  • SIGLEC-3
  • SIGLEC3
  • p67
Reactivity
Human
400
30
26
16
8
2
2
Host
Mouse
309
110
1
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
53
49
28
18
6
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
232
178
88
66
57
56
31
30
26
22
19
12
4
3
2
2
1
1
1
Supplier
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Immunogen Purified recombinant fragment of CD33 (48-258) expressed in E. coli.
Clone 2B7C12
Isotype IgG1
Purification Ascites
Alternative Name CD33 (CD33 Antibody Abstract)
Background CD33 is found on granulocyte and macrophage precursors in the bone marrow, but is not on pluripotent stem cells. The protein is also expressed on, and is a useful marker for, peripheral monocytes. It is also useful for distinguishing myelogenous leukaemia cells from lymphoid or erythroid leukaemias.
Gene ID 945
HGNC 945
Research Area Stem Cells, Hematopoietic Progenitors, Hematopoietic Stem Cells, CD Antigens, Surface Receptors of Immune Cells
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
Western Blotting (WB) image for anti-CD33 Molecule (CD33) antibody (ABIN969020) Figure 1: Western blot analysis using CD33 mouse mAb against truncated Trx-CD33 recom...
Product cited in: Plesa, Chelghoum, Plesa et al.: "Prognostic value of immunophenotyping in elderly patients with acute myeloid leukemia: a single-institution experience." in: Cancer, Vol. 112, Issue 3, pp. 572-80, 2008 (PubMed).

Balaian, Ball: "Anti-CD33 monoclonal antibodies enhance the cytotoxic effects of cytosine arabinoside and idarubicin on acute myeloid leukemia cells through similarities in their signaling pathways." in: Experimental hematology, Vol. 33, Issue 2, pp. 199-211, 2005 (PubMed).