CD34 antibody (CD34 Molecule)

Details for Product anti-CD34 Antibody No. ABIN969021, Supplier: Log in to see
Antigen
  • AU040960
  • CD34 antigen
  • CD34 molecule
  • LOC100343670
  • Cd34
  • CD34
Reactivity
Human
803
239
158
73
45
32
31
12
11
9
8
5
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4
3
2
2
2
2
2
Host
Mouse
643
210
114
11
7
3
3
Clonality (Clone)
Monoclonal ()
Conjugate
This CD34 antibody is un-conjugated
96
85
54
28
26
22
20
19
17
17
17
12
11
11
11
11
11
11
9
9
9
6
5
4
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
702
446
334
201
172
145
122
120
119
39
17
14
14
13
13
12
8
8
8
6
5
4
2
2
1
1
1
1
1
1
1
1
Options
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Immunogen Purified recombinant fragment of CD34 expressed in E. Coli.
Clone 4H5E7
Isotype IgG2b
Purification Ascites
Alternative Name CD34 (CD34 Antibody Abstract)
Background CD34 is a transmembrane glycoprotein with a molecular mass of approximately 110 kD that is selectively expressed on human hematopoietic progenitor cells, endothelial cells and some fibroblasts. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is highly expressed on hematopoietic progenitors, as well as on endothelial cells. CD34 has been used to measure angiogenesis, which reportedly predicts tumor recurrence.
Gene ID 947
HGNC 947
Research Area Hematopoietic Progenitors, Hematopoietic Stem Cells, Cardiogenesis, Lineage Markers, CD Antigens, Surface Receptors of Immune Cells
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Immunocytochemistry (ICC) image for anti-CD34 antibody (CD34 Molecule) (ABIN969021) Figure 1: Immunofluorescence analysis of peripheral blood cells using CD34 mouse mAb.
Immunohistochemistry (IHC) image for anti-CD34 antibody (CD34 Molecule) (ABIN969021) Figure 2: Immunohistochemical analysis of paraffin-embedded human spleen using CD34 m...
Western Blotting (WB) image for anti-CD34 antibody (CD34 Molecule) (ABIN969021) Figure 3: Western blot analysis using CD34 mouse mAb against truncated CD34 recombina...
Product cited in: Sho, Sho, Nanjo, Kawamura, Masuda, Dalman: "Hemodynamic regulation of CD34+ cell localization and differentiation in experimental aneurysms." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 24, Issue 10, pp. 1916-21, 2004 (PubMed).

Background publications Krause, Ito, Fackler, Smith, Collector, Sharkis, May: "Characterization of murine CD34, a marker for hematopoietic progenitor and stem cells." in: Blood, Vol. 84, Issue 3, pp. 691-701, 1994 (PubMed).

Satterthwaite, Burn, Le Beau, Tenen: "Structure of the gene encoding CD34, a human hematopoietic stem cell antigen." in: Genomics, Vol. 12, Issue 4, pp. 788-94, 1992 (PubMed).