N-Cadherin antibody
(2 references)-
- Target See all N-Cadherin (CDH2) Antibodies
- N-Cadherin (CDH2) (Cadherin 2 (CDH2))
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Reactivity
- Human, Mouse, Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This N-Cadherin antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human CDH2 expressed in E. coli.
- Clone
- 5D5
- Isotype
- IgG1
- Top Product
- Discover our top product CDH2 Primary Antibody
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anti-Cadherin 2 (CDH2) (AA 701-800) antibody
CDH2 Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio) WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Cadherin 2 (CDH2) antibodyCDH2 Reactivity: Human, Mouse, Dog, Monkey WB, IHC, FACS, IHC (p) Host: Mouse Monoclonal 2G7 unconjugated
anti-Cadherin 2 (CDH2) (AA 750-850) antibodyCDH2 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Cadherin 2 (CDH2) antibodyKO Validated CDH2 Reactivity: Human WB, IHC, IF Host: Rabbit Monoclonal unconjugated
anti-Cadherin 2 (CDH2) (AA 690-770) antibodyCDH2 Reactivity: Human, Mouse, Rat WB, IF, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Cadherin 2 (CDH2) (AA 45-238) antibodyCDH2 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Cadherin 2 (CDH2) antibodyCDH2 Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Cadherin 2 (CDH2) antibodyCDH2 Reactivity: Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Cadherin 2 (CDH2) (AA 450-550) antibodyCDH2 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Cadherin 2 (CDH2) (AA 685-784) antibodyCDH2 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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: "Phospho-Akt pathway activation and inhibition depends on N-cadherin or phospho-EGFR expression in invasive human bladder cancer cell lines." in: Urologic oncology, Vol. 28, Issue 2, pp. 180-8, (2010) (PubMed).
: "IQ-domain GTPase-activating protein 1 regulates beta-catenin at membrane ruffles and its role in macropinocytosis of N-cadherin and adenomatous polyposis coli." in: The Journal of biological chemistry, Vol. 282, Issue 11, pp. 8545-56, (2007) (PubMed).
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: "Phospho-Akt pathway activation and inhibition depends on N-cadherin or phospho-EGFR expression in invasive human bladder cancer cell lines." in: Urologic oncology, Vol. 28, Issue 2, pp. 180-8, (2010) (PubMed).
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- Target
- N-Cadherin (CDH2) (Cadherin 2 (CDH2))
- Alternative Name
- CDH2 (CDH2 Products)
- Background
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Description: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.
Aliases: CDHN, NCAD, CD325, CDw325, CDH2
- Molecular Weight
- 99.8 kDa
- Gene ID
- 1000
- HGNC
- 1000
- Pathways
- Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane
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