CEBPB antibody

Catalog No. ABIN969049

Product Details anti-CEBPB Antibody

Target: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CEBPB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purification: purified

Immunogen: Purified recombinant fragment of human CEBPB expressed in E. coli.

Clone: 3H9

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

References for anti-CEBPB antibody (ABIN969049)

Cappello, Zwergal, Kanclerski, Haas, Kandemir, Huber, Page, Brand: "C/EBPbeta enhances NF-kappaB-associated signalling by reducing the level of IkappaB-alpha." in: Cellular signalling, Vol. 21, Issue 12, pp. 1918-24, (2009) (PubMed).

Target Details for CEBPB

Target: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Alternative Name: CEBPB (CEBPB Products)

Synonyms: C/EBPbeta antibody, c/ebp-beta antibody, crp2 antibody, il6dbp antibody, lap antibody, nf-il6 antibody, tcf5 antibody, xC/EBPbeta antibody, cebpbb antibody, cb380 antibody, c/ebpb antibody, fe11e05 antibody, wu:fe11e05 antibody, CEBPB antibody, LOC100136165 antibody, C/EBP-beta antibody, CRP2 antibody, IL6DBP antibody, LAP antibody, NF-IL6 antibody, TCF5 antibody, IL-6DBP antibody, LIP antibody, NF-M antibody, Nfil6 antibody, Il6dbp antibody, CCAAT/enhancer binding protein beta antibody, CCAAT/enhancer binding protein beta L homeolog antibody, CCAAT/enhancer binding protein (C/EBP), beta antibody, CCAAT/enhancer-binding protein beta antibody, cebpb antibody, cebpb.L antibody, CEBPB antibody, LOC100136165 antibody, Cebpb antibody

Background:

Description: The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. Tissue specificity: Expressed at low levels in the lung, kidney and spleen.

Aliases: LAP, CRP2, TCF5, IL6DBP, NF-IL6, MGC32080, C/EBP-beta

Molecular Weight: 36 kDa

Gene ID: 1051

HGNC: 1051

Pathways: Interferon-gamma Pathway, Autophagy, Brown Fat Cell Differentiation