CHUK antibody (conserved Helix-Loop-Helix Ubiquitous Kinase) (AA 500-590)

Details for Product anti-CHUK Antibody No. ABIN969054, Supplier: Log in to see
Antigen
  • ikk
  • ikk1
  • ikka
  • ikkalpha
  • CHUK
  • IKBKA
  • IKK-alpha
  • IKK1
  • IKKA
  • NFKBIKA
  • TCF16
  • AI256658
  • Chuk1
  • Fbx24
  • Fbxo24
  • Ikka
  • zgc:56539
  • conserved helix-loop-helix ubiquitous kinase
  • chuk
  • CHUK
  • Chuk
Alternatives
anti-Human CHUK antibody for Western Blotting
Epitope
AA 500-590
51
32
17
17
15
15
11
11
10
9
9
8
8
8
7
7
7
7
6
5
4
3
3
3
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
353
154
105
20
12
11
10
7
6
5
5
4
2
1
Host
Mouse
274
82
12
1
Clonality (Clone)
Monoclonal ()
Conjugate
This CHUK antibody is un-conjugated
15
11
11
9
8
8
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
318
150
95
78
62
48
44
29
26
19
9
5
3
3
2
2
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen Purified recombinant fragment of CHUK (aa500-590) expressed in E. Coli.
Clone 7C10B6
Isotype IgG1
Purification Ascites
Alternative Name CHUK (CHUK Antibody Abstract)
Background CHUK: conserved helix-loop-helix ubiquitous kinase. This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.
Gene ID 1147
HGNC 1147
Pathways PI3K-Akt Signaling, NF-kappaB Signaling, RTK Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Western Blotting (WB) image for anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (AA 500-590) antibody (ABIN969054) Figure 1: Western blot analysis using CHUK mouse mAb against truncated Trx-CHUK recom...
Product cited in: Prajapati, Verma, Yamamoto, Kwak, Gaynor: "Protein phosphatase 2Cbeta association with the IkappaB kinase complex is involved in regulating NF-kappaB activity." in: The Journal of biological chemistry, Vol. 279, Issue 3, pp. 1739-46, 2004 (PubMed).

Background publications Soond, Terry, Colbert, Riches: "TRUSS, a novel tumor necrosis factor receptor 1 scaffolding protein that mediates activation of the transcription factor NF-kappaB." in: Molecular and cellular biology, Vol. 23, Issue 22, pp. 8334-44, 2003 (PubMed).

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