You are viewing an incomplete version of our website. Please click to reload the website as full version.

CHUK antibody (conserved Helix-Loop-Helix Ubiquitous Kinase) (AA 500-590)

Details for Product anti-CHUK Antibody No. ABIN969054, Supplier: Login to see
Antigen
  • ikk
  • ikk1
  • ikka
  • ikkalpha
  • CHUK
  • IKBKA
  • IKK-alpha
  • IKK1
  • IKKA
  • NFKBIKA
  • TCF16
  • AI256658
  • Chuk1
  • Fbx24
  • Fbxo24
  • Ikka
  • zgc:56539
Alternatives
anti-Human CHUK antibody for Western Blotting
Epitope
AA 500-590
60
27
22
16
15
15
14
12
12
11
10
10
8
8
8
8
7
6
4
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
308
96
71
2
2
Host
Mouse
261
51
10
2
Clonality (Clone)
Monoclonal ()
Conjugate
This CHUK antibody is un-conjugated
14
10
10
8
8
8
2
2
2
2
2
2
2
2
Application
ELISA, Western Blotting (WB)
283
137
86
43
42
37
33
20
10
9
4
2
2
1
1
1
Supplier
Login to see
Supplier Product No.
Login to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen Purified recombinant fragment of CHUK (AA 500-590) expressed in E. coli.
Clone 7C10B6
Isotype IgG1
Purification Ascites
Alternative Name CHUK (CHUK Antibody Abstract)
Background CHUK: conserved helix-loop-helix ubiquitous kinase. This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.
Gene ID 1147
HGNC 1147
Pathways PI3K-Akt Signaling, NF-kappaB Signaling, RTK Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
Western Blotting (WB) image for anti-CHUK antibody (conserved Helix-Loop-Helix Ubiquitous Kinase) (AA 500-590) (ABIN969054) Figure 1: Western blot analysis using CHUK mouse mAb against truncated Trx-CHUK recom...
Product cited in: Prajapati, Verma, Yamamoto et al.: "Protein phosphatase 2Cbeta association with the IkappaB kinase complex is involved in regulating NF-kappaB activity." in: The Journal of biological chemistry, Vol. 279, Issue 3, pp. 1739-46, 2004 (PubMed).

Background publications Soond, Terry, Colbert et al.: "TRUSS, a novel tumor necrosis factor receptor 1 scaffolding protein that mediates activation of the transcription factor NF-kappaB." in: Molecular and cellular biology, Vol. 23, Issue 22, pp. 8334-44, 2003 (PubMed).