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DKK1 antibody

DKK1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2H2 unconjugated
Catalog No. ABIN969085
  • Target See all DKK1 Antibodies
    DKK1 (Dickkopf Homolog 1 (DKK1))
    Reactivity
    • 125
    • 33
    • 29
    • 18
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 121
    • 11
    • 1
    • 1
    Mouse
    Clonality
    • 113
    • 21
    Monoclonal
    Conjugate
    • 60
    • 14
    • 11
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DKK1 antibody is un-conjugated
    Application
    • 91
    • 52
    • 25
    • 18
    • 14
    • 13
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    purified
    Immunogen
    Purified recombinant fragment of DKK1 expressed in E. coli.
    Clone
    2H2
    Isotype
    IgG2b
    Top Product
    Discover our top product DKK1 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Yamamoto, Sakane, Yamamoto, Michiue, Kikuchi: "Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of beta-catenin signaling." in: Developmental cell, Vol. 15, Issue 1, pp. 37-48, (2008) (PubMed).

    Qiao, Xu, Zhao, Ye, Zhang: "Dkk-1 secreted by mesenchymal stem cells inhibits growth of breast cancer cells via depression of Wnt signalling." in: Cancer letters, Vol. 269, Issue 1, pp. 67-77, (2008) (PubMed).

  • Target
    DKK1 (Dickkopf Homolog 1 (DKK1))
    Alternative Name
    DKK1 (DKK1 Products)
    Synonyms
    DKK-1 antibody, SK antibody, AI414495 antibody, SGY antibody, SGY-1 antibody, SGY1 antibody, Soggy antibody, mSgy antibody, dkk1 antibody, dkk antibody, dkk-1 antibody, xdkk1 antibody, Xdkk-1 antibody, Dickkopf1 antibody, dickkopf-1 antibody, mdkk-1 antibody, dkk1-A antibody, dickkopf WNT signaling pathway inhibitor 1 antibody, dickkopf like acrosomal protein 1 antibody, dickkopf-related protein 1 antibody, dickkopf-like 1 antibody, dickkopf WNT signaling pathway inhibitor 1b antibody, dickkopf protein antibody, dickkopf WNT signaling pathway inhibitor 1 S homeolog antibody, DKK1 antibody, Dkk1 antibody, DKKL1 antibody, LOC100228789 antibody, Dkkl1 antibody, dkk1b antibody, dkk1 antibody, dickkopf antibody, dkk1.S antibody
    Background

    Description: DKK1: dickkopf homolog 1 (Xenopus laevis), also known as SK. Entrez Protein NP_036374. DKK1 is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.

    Aliases: SK, DKK-1,

    Molecular Weight
    28.7 kDa
    Gene ID
    22943
    HGNC
    22943
    Pathways
    WNT Signaling, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation
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