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ENOS antibody (Nitric Oxide Synthase 3 (Endothelial Cell))

Details for Product anti-NOS3 Antibody No. ABIN969097, Supplier: Log in to see
Antigen
  • NOS3
  • ECNOS
  • eNOS
  • NOS
  • EC-NOS
  • NOSIII
  • cNOS
  • 2310065A03Rik
  • Nos-3
  • ecNOS
  • eNos
  • ENOS
Alternatives
anti-Human ENOS antibody for Enzyme Immunoassay
Reactivity
Human
375
208
194
31
31
11
11
9
2
2
2
1
1
1
Host
Mouse
408
38
Clonality (Clone)
Monoclonal ()
Conjugate
This ENOS antibody is un-conjugated
28
25
17
8
7
7
6
6
6
6
6
6
6
6
6
Application
Immunohistochemistry (IHC), ELISA
283
166
68
68
57
53
24
23
23
19
11
7
5
2
2
1
1
Supplier
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Immunogen Purified recombinant fragment of human eNOS expressed in E. coli.
Clone 6H2
Isotype IgG1
Purification Ascites
Alternative Name eNOS (NOS3 Antibody Abstract)
Background Endothelial nitric-oxide synthase (eNOS), also known as NOS3, it is an important enzyme in the cardiovascular system. It is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm.
Molecular Weight 133 kDa
Gene ID 4846
HGNC 4846
Research Area Cancer, Enzymes, Metabolism, Inflammation
Pathways ACE Inhibitor Pathway
Application Notes Recommended Dilution:
ELISA: 1/10000, IHC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
Immunohistochemistry (IHC) image for anti-ENOS antibody (Nitric Oxide Synthase 3 (Endothelial Cell)) (ABIN969097) Figure 1: Immunohistochemical analysis of paraffin-embedded human stomach cancer (lef...
Immunohistochemistry (IHC) image for anti-ENOS antibody (Nitric Oxide Synthase 3 (Endothelial Cell)) (ABIN969097) Figure 2: Immunohistochemical analysis of paraffin-embedded human lymph node (left) a...
Product cited in: Moreno: "Genetic polymorphisms and haplotypes of eNOS in breast cancer." in: Breast cancer research and treatment, Vol. 109, Issue 1, pp. 181-2, 2008 (PubMed).

Lahiri, Martin: "Reduced expression of endothelial and inducible nitric oxide synthase in a multidrug resistant variant of the MCF-7 human breast cancer cell line." in: Oncology reports, Vol. 12, Issue 5, pp. 1007-11, 2004 (PubMed).

Background publications Dimmeler, Fleming, Fisslthaler et al.: "Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation." in: Nature, Vol. 399, Issue 6736, pp. 601-5, 1999 (PubMed).