ENOS antibody (Nitric Oxide Synthase 3 (Endothelial Cell))

Details for Product anti-NOS3 Antibody No. ABIN969097, Supplier: Log in to see
Antigen
  • NOS3
  • ECNOS
  • eNOS
  • NOS
  • EC-NOS
  • NOSIII
  • cNOS
  • 2310065A03Rik
  • Nos-3
  • ecNOS
  • eNos
  • ENOS
  • nitric oxide synthase 3 (endothelial cell)
  • endothelial nitric oxide synthase
  • nitric oxide synthase 3, endothelial cell
  • NOS3
  • nos3
  • 23B
  • Nos3
Alternatives
anti-Human ENOS antibody for BioImaging
Reactivity
Human
404
251
244
48
46
40
21
16
7
6
6
2
2
2
2
2
2
1
1
Host
Mouse
416
55
Clonality (Clone)
Monoclonal ()
Conjugate
This ENOS antibody is un-conjugated
28
25
17
8
7
7
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), ELISA
323
185
81
78
76
74
32
25
24
18
11
10
5
3
2
2
1
1
Options
Supplier
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Immunogen Purified recombinant fragment of human eNOS expressed in E. Coli.
Clone 6H2
Isotype IgG1
Purification Ascites
Alternative Name eNOS (NOS3 Antibody Abstract)
Background Endothelial nitric-oxide synthase (eNOS), also known as NOS3, it is an important enzyme in the cardiovascular system. It is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm.
Molecular Weight 133 kDa
Gene ID 4846
HGNC 4846
Research Area Cancer, Enzymes, Metabolism, Inflammation
Pathways ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals
Application Notes ELISA: 1:10000, IHC: 1:200 - 1:1000
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Immunohistochemistry (IHC) image for anti-ENOS antibody (Nitric Oxide Synthase 3 (Endothelial Cell)) (ABIN969097) Figure 1: Immunohistochemical analysis of paraffin-embedded human stomach cancer (lef...
Immunohistochemistry (IHC) image for anti-ENOS antibody (Nitric Oxide Synthase 3 (Endothelial Cell)) (ABIN969097) Figure 2: Immunohistochemical analysis of paraffin-embedded human lymph node (left) a...
Product cited in: Moreno: "Genetic polymorphisms and haplotypes of eNOS in breast cancer." in: Breast cancer research and treatment, Vol. 109, Issue 1, pp. 181-2, 2008 (PubMed).

Lahiri, Martin: "Reduced expression of endothelial and inducible nitric oxide synthase in a multidrug resistant variant of the MCF-7 human breast cancer cell line." in: Oncology reports, Vol. 12, Issue 5, pp. 1007-11, 2004 (PubMed).

Background publications Dimmeler, Fleming, Fisslthaler, Hermann, Busse, Zeiher: "Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation." in: Nature, Vol. 399, Issue 6736, pp. 601-5, 1999 (PubMed).